Results 61 to 70 of about 3,839 (161)

Case Report of Combined Central and Peripheral Demyelination: Treated With Ofatumumab

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background and Objectives Combined central and peripheral demyelination (CCPD) is a rare autoimmune‐mediated disorder characterized by demyelination affecting both the central nervous system and peripheral nervous system. The involvement of the CNS typically manifests as longitudinally extensive transverse myelitis and optic neuritis, whereas ...
Lili Liu, Zhigang Zhong, Haijun Wu, Jun Hu, Juanjuan Chen   +4 more
wiley   +1 more source

Novel LAMA1 Mutations in a Pedigree With Poretti‐Boltshauser Syndrome: Implications for Hypomyelination

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
This study reports novel compound heterozygous LAMA1 variants in two siblings with Poretti‐Boltshauser syndrome presenting with cerebral hypomyelination. It provides the first clinical evidence linking LAMA1 to CNS dysmyelination, expanding the phenotypic spectrum and offering mechanistic insights into this rare association. ABSTRACT Background Poretti‐
Si Huang, Yiyang Li, Jing Xin, Wenhui Mo, Xiuwen Lin, Bingbin Mai, Junbin He, Xiaoli Zhong, Jiaxin Xu   +8 more
wiley   +1 more source

Evaluation Of The Role Of Visual Evoked Potentials In Detecting Visual Impairment In Type II Diabetes Mellitus

Delhi Journal of Ophthalmology, 2018
Purpose:- To investigate the visual evoked potentials in Type II diabetic patients in order to determine the alterations, if any, resulting from visual impairment due to diabetes mellitus (DM).
Ruchi Kothari, Pradeep Bokariya, Smita Singh, TS Hemavaishnave   +3 more
doaj   +1 more source

Homozygous Pathogenic Variant in Elongation Factor‐Like 1 (EFL1) as a Causal Factor in Shwachman‐Diamond Syndrome 2 in a Palestinian Child, With Distinct Ocular Manifestations

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
We report a Palestinian female infant with a homozygous pathogenic EFL1 variant (c.3284G>A; p.Arg1095Gln) causing Shwachman–Diamond syndrome type 2 (SDS2). Beyond the classical features of pancytopenia, exocrine pancreatic insufficiency, and growth failure, the patient showed previously unreported ocular manifestations—stage 2–3 retinopathy of ...
Ibrahim Taha, Antonella Minelli, Cesare Danesino, Abdelrahman Swalmeh, Khalil Huraibat, Liana Al‐Labadi, Rema Obar, Khaled R. Beshtawi, Lubna Abu Samrah, Yousef Awlad Mohammad, Aya Farah, Abdulrahman Obar, Mutasem Khalaf, Orwa Nasser   +13 more
wiley   +1 more source

The Comparison of VEP Parameters in Neuromyelitis Optica Spectrum Disorders and Multiple Sclerosis Patients with Acute Optic Neuritis

Neuropsychiatric Investigation, 2020
Introduction: Multiple sclerosis (MS) and neuromyelitisoptica spectrum disorders (NMOSD) are idiopathic, autoimmune, and centralnervous system inflammatory diseases.
Nilda TURGUT, Bengü ALTUNAN, Aslı AKSOY GÜNDOĞDU   +2 more
doaj   +1 more source

Conscious Tactile Perception Depends on Early Processing in Primary Somatosensory Cortex

European Journal of Neuroscience, Volume 63, Issue 10, May 2026.
Single‐pulse TMS over the contralateral primary somatosensory cortex (S1) impaired tactile sensitivity at early (25 and 75 ms), but not late (130 ms) latencies following electrotactile stimulation of the finger at the sensory detection threshold, demonstrating a temporally constrained role of S1 in conscious detection. TMS did not have any interference
Louisa Gwynne, Luigi Tamè
wiley   +1 more source

Role of Visual Evoked Potential as a Screening Tool for Subclinical Optic Neuropathy in Patients with Diabetes Mellitus: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Diabetes poses a major health challenge in India, with rising cases leading to serious complications like optic neuropathy and vision loss. These conditions often remain silent in the early stages, making timely detection crucial.
Abhishek Kumar Jaiswal, Anil Kumar, Navneet Kumar Kaushik, Jeevan Deep Dande   +3 more
doaj   +1 more source

Pattern Visual Evoked Potentials in Patients with Type II Diabetes Mellitus

Journal of Ophthalmic & Vision Research, 2012
Purpose: To evaluate cortical and retinal activity by pattern visual evoked potentials (PVEP) in patients with type II diabetes mellitus. Methods: PVEP was recorded in 40 diabetic patients including 20 subjects with nonproliferative diabetic retinopathy
Javad Heravian, Akram Ehyaei, Nasser Shoeibi, Abbass Azimi, Hadi Ostadi-Moghaddam, Abbas-Ali Yekta, Mohamad Javad Khoshsima, Habbibolah Esmaily   +7 more
doaj  

Gender differences and correlates of visual evoked potential parameters with head circumference: A comparative analysis

National Journal of Physiology, Pharmacy and Pharmacology
Background: Evoked potentials are electrical events recorded in the cerebral cortex after stimulation of a sense organ. They are non-invasive studies used to assess visual conduction pathways through optic nerves and the brain.
Hetalben P Zala, Anju S Mehta
doaj   +1 more source

Latency-shift of intra-operative visual evoked potential predicts reversible homonymous hemianopia after intra-ventricular meningioma surgery

Clinical Neurophysiology Practice, 2019
Objectives: Intraoperative visual evoked potentials (VEPs) are used to monitor the function of optic radiation during neurosurgery with the P100 amplitude decrement as a predictor of post-operative visual deficit.
Erisela Qerama, Anders R. Korshoej, Mikkel V. Petersen, Richard Brandmeier, Gorm von Oettingen   +4 more
doaj   +1 more source