Results 1 to 10 of about 57,796 (112)

PI3 kinase signaling pathway in hematopoietic cancers: A glance in miRNA's role. [PDF]

J Clin Lab Anal, 2021
PI3K pathway involves in a wide verity of important biological events in cells such as proliferation, differentiation, apoptosis, and even drug resistance. It is confirmed that there is a relationship between dysregulation of mediators involved in this signaling pathway and different cancer types such as hematopoietic malignancies.
Roshandel E, Noorazar L, Farhadihosseinabadi B, Mehdizadeh M, Kazemi MH, Parkhideh S.   +5 more
europepmc   +2 more sources

Lactiplantibacillus plantarum P101 Attenuated Cyclophosphamide-Induced Liver Injury in Mice by Regulating the Nrf2/ARE Signaling Pathway

International Journal of Molecular Sciences, 2023
Cyclophosphamide causes side effects in cancer patients, including hepatotoxicity. Probiotics have recently emerged as potential approaches for the administration of many diseases.
T. You, Yu Zhao, Shanji Liu, Hengyi Xu
semanticscholar   +1 more source

The Molecular Mechanism of the TEAD1 Gene and miR-410-5p Affect Embryonic Skeletal Muscle Development: A miRNA-Mediated ceRNA Network Analysis

Cells, 2023
Muscle development is a complex biological process involving an intricate network of multiple factor interactions. Through the analysis of transcriptome data and molecular biology confirmation, this study aims to reveal the molecular mechanism underlying
Wenping Hu, Xinyue Wang, Yazhen Bi, J. Bao, Mingyu Shang, Li Zhang   +5 more
semanticscholar   +1 more source

Lactiplantibacillus plantarum P101 alleviates alcoholic liver injury by modulating the Nrf2/HO-1 pathway in mice.

Journal of Applied Microbiology, 2022
AIMS The occurrence of alcoholic liver injury is related to the oxidative stress. Bacteria for alleviating alcoholic related liver injury have received widespread attention.
Shanji Liu, Yu Zhao, Xiaowei Xu, Mengqi Wang, X. Tao, Hengyi Xu   +5 more
semanticscholar   +1 more source

Le pouvoir impérial et les religions dans l’Empire (284-410)

Gouverner un empire de 284 à 410 apr. J.-C., 2023
Pour comprendre les relations complexes entre le pouvoir impérial et les religions entre 284 et 410, il convient d’abord d’évoquer la définition religieuse de l’autorité impériale.
Christophe J. Goddard
semanticscholar   +1 more source

Detection and Analysis of Corrosion and Contact Resistance Faults of TiN and CrN Coatings on 410 Stainless Steel as Bipolar Plates in PEM Fuel Cells

Italian National Conference on Sensors, 2022
Bipolar Plates (BPPs) are the most crucial component of the Polymer Electrolyte Membrane (PEM) fuel cell system. To improve fuel cell stack performance and lifetime, corrosion resistance and Interfacial Contact Resistance (ICR) enhancement are two ...
Mohsen Forouzanmehr, Kazem Reza Kashyzadeh, A. Borjali, Anastas Ivanov, Mosayeb Jafarnode, T. Gan, Bin Wang, M. Chizari   +7 more
semanticscholar   +1 more source

Inhibition of LncRNA-NEAT1 alleviates intestinal epithelial cells (IECs) dysfunction in ulcerative colitis by maintaining the homeostasis of the glucose metabolism through the miR-410-3p-LDHA axis

Bioengineered, 2022
Dysfunction of intestinal epithelial cells (IECs) leads to intestinal epithelial barrier damage and critically involves in the pathogenesis and development of ulcerative colitis (UC).
Siyi Ni, Yingchao Liu, Jihong Zhong, Yan Shen   +3 more
semanticscholar   +1 more source

Droit et gouvernement de l’Empire (284-410 apr. J.-C.)

Gouverner un empire de 284 à 410 apr. J.-C., 2023
L’expérience juridique de l’Antiquité tardive est marquée par la centralité de l’empereur dans la production normative, à travers les constitutions impériales. La transmission de ces dernières par le Code Théodosien a favorisé un biais, qui focalise l’
Hélène Ménard
semanticscholar   +1 more source

Le pouvoir et les populations extérieures à l’Empire (284-410 apr. J.-C.)

Gouverner un empire de 284 à 410 apr. J.-C., 2023
Les travaux concernant les barbares au xxie siècle cherchent à dépasser la répétition du discours romain, qui perpétue la vision d’un empereur éternellement victorieux contre des menaces barbares perpétuelles et identiques, tout en considérant que ...
Magali Coumert
semanticscholar   +1 more source

Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation

Science Advances, 2021
The structure of class IB PI3K (p110γ-p101) reveals mechanism of GPCR activation and differences from class IA PI3Ks.
M. Rathinaswamy, U. Dalwadi, Kaelin D. Fleming, Carson Adams, Jordan T B Stariha, E. Pardon, M. Baek, O. Vadas, F. DiMaio, J. Steyaert, Scott D. Hansen, C. Yip, J. Burke   +12 more
semanticscholar   +1 more source