Results 11 to 20 of about 169,296 (215)

PI3 kinase signaling pathway in hematopoietic cancers: A glance in miRNA's role. [PDF]

J Clin Lab Anal, 2021
PI3K pathway involves in a wide verity of important biological events in cells such as proliferation, differentiation, apoptosis, and even drug resistance. It is confirmed that there is a relationship between dysregulation of mediators involved in this signaling pathway and different cancer types such as hematopoietic malignancies.
Roshandel E, Noorazar L, Farhadihosseinabadi B, Mehdizadeh M, Kazemi MH, Parkhideh S.   +5 more
europepmc   +2 more sources

Immunomodulatory Mechanisms of Rehmanniae Radix Praeparata-Achyranthes Root-Chinese Angelica Root Combination in Nontraumatic Osteonecrosis of the Femoral Head: A Comprehensive Network Pharmacology and Molecular Docking Study Focusing on Immunological Pathways. [PDF]

Mediators Inflamm
Objective Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating condition characterised by immune dysregulation and sterile inflammation, which are increasingly acknowledged as central pathogenic mechanisms. This study aims to identify the core herbal combination for NONFH and systematically explore its immunomodulatory effects and ...
Li X, Ng L, Liu C, Qin L, Xiao P, Liu C, Liu Y, Zhang Q, Huang W, Zhou Y.   +9 more
europepmc   +2 more sources

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment. [PDF]

MedComm (2020)
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Jiang M, Zhang K, Zhang Z, Zeng X, Huang Z, Qin P, Xie Z, Cai X, Ashrafizadeh M, Tian Y, Wei R.   +10 more
europepmc   +2 more sources

The Molecular Mechanism of the TEAD1 Gene and miR-410-5p Affect Embryonic Skeletal Muscle Development: A miRNA-Mediated ceRNA Network Analysis

Cells, 2023
Muscle development is a complex biological process involving an intricate network of multiple factor interactions. Through the analysis of transcriptome data and molecular biology confirmation, this study aims to reveal the molecular mechanism underlying
Wenping Hu, Xinyue Wang, Yazhen Bi, J. Bao, Mingyu Shang, Li Zhang   +5 more
semanticscholar   +1 more source

Le pouvoir impérial et les religions dans l’Empire (284-410)

Gouverner un empire de 284 à 410 apr. J.-C., 2023
Pour comprendre les relations complexes entre le pouvoir impérial et les religions entre 284 et 410, il convient d’abord d’évoquer la définition religieuse de l’autorité impériale.
Christophe J. Goddard
semanticscholar   +1 more source

Lactiplantibacillus plantarum P101 alleviates alcoholic liver injury by modulating the Nrf2/HO-1 pathway in mice.

Journal of Applied Microbiology, 2022
AIMS The occurrence of alcoholic liver injury is related to the oxidative stress. Bacteria for alleviating alcoholic related liver injury have received widespread attention.
Shanji Liu, Yu Zhao, Xiaowei Xu, Mengqi Wang, X. Tao, Hengyi Xu   +5 more
semanticscholar   +1 more source

The Most Problematic Aspects of American Pronunciation for Polish Learners of English with and without Prior Phonetic Training [PDF]

Beiträge zur Allgemeinen und Vergleichenden Sprachwissenschaft, 2023
Previous research on the topic of contrastive phonetics and phonology of Polish and English and studies of pronunciation errors focused only on British RP without examining General American (GA).
Paweł Lisik
doaj   +1 more source

Detection and Analysis of Corrosion and Contact Resistance Faults of TiN and CrN Coatings on 410 Stainless Steel as Bipolar Plates in PEM Fuel Cells

Italian National Conference on Sensors, 2022
Bipolar Plates (BPPs) are the most crucial component of the Polymer Electrolyte Membrane (PEM) fuel cell system. To improve fuel cell stack performance and lifetime, corrosion resistance and Interfacial Contact Resistance (ICR) enhancement are two ...
M. Forouzanmehr, Kazem Reza Kashyzadeh, A. Borjali, Anastas Ivanov, Mosayeb Jafarnode, T. Gan, Bin Wang, M. Chizari   +7 more
semanticscholar   +1 more source

Exploring subjective well-being of older adult foreign language learners: Results of a pilot study [PDF]

Beiträge zur Allgemeinen und Vergleichenden Sprachwissenschaft, 2023
Societies are ageing and there is a growing desire in people aged 60 and more to continue their education in late adulthood. Yet, there is still a scarcity of research related to Foreign Language Geragogy and to the relationship between well-being and ...
Agata Słowik-Krogulec
doaj   +1 more source

Neue Interjektionen im Deutschen und im deutsch- -französisch-italienischen Sprachvergleich. Eine deskriptive und kontrastive Korpusstudie [PDF]

Beiträge zur Allgemeinen und Vergleichenden Sprachwissenschaft, 2023
This paper investigates the functions of new interjections “oops/ups”, “wtf”, and “yep” by means of a corpus-based approach. The samples for the monolingual and contrastive analyses were selected from DeReKo und Czech National Corpus.
Sabrina Ghislandi, Chloé Rustan
doaj   +1 more source