PI3 kinase signaling pathway in hematopoietic cancers: A glance in miRNA's role. [PDF]
J Clin Lab Anal, 2021 PI3K pathway involves in a wide verity of important biological events in cells such as proliferation, differentiation, apoptosis, and even drug resistance. It is confirmed that there is a relationship between dysregulation of mediators involved in this signaling pathway and different cancer types such as hematopoietic malignancies.
Roshandel E +5 more
europepmc +2 more sources
Immunomodulatory Mechanisms of Rehmanniae Radix Praeparata-Achyranthes Root-Chinese Angelica Root Combination in Nontraumatic Osteonecrosis of the Femoral Head: A Comprehensive Network Pharmacology and Molecular Docking Study Focusing on Immunological Pathways. [PDF]
Mediators InflammObjective Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating condition characterised by immune dysregulation and sterile inflammation, which are increasingly acknowledged as central pathogenic mechanisms. This study aims to identify the core herbal combination for NONFH and systematically explore its immunomodulatory effects and ...
Li X +9 more
europepmc +2 more sources
PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment. [PDF]
MedComm (2020)The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Jiang M +10 more
europepmc +2 more sources
Studi var an astrou (1848) : des Lumières dans l’ombre
La Bretagne Linguistique, 2022 Studi var an astrou (Brest, Lefournier, 1848) is probably the first scientific text in Breton. Publishing an astronomical treatise to educate the Breton population, in the middle of a 19th century literary marked by Bretonism and neo-Bardism, is a rare ...
Nelly Blanchard
doaj +1 more source
, 2021 Partial family P101 pedigree that displays the 16 individuals that were included in this study. These included five affected males (bipolar disorder I: 700, 685, 691, 698, major depression: 686) and two affected females (bipolar disorder I: 699, major ...
William J. Rowell (6930539) +11 more
core +1 more source
Språkpolitikk og (u)synleggjering i det semiotiske landskapet på Universitetet i Tromsø
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2013 I denne artikkelen analyserer vi det semiotiske landskapet som famnar om og er ein del av staden Universitetet i Tromsø (UiT), inkludert Universitetssykehuset Nord-Norge (UNN).
Åse Mette Johansen, Tove Bull
doaj +1 more source
Sequence-of-tense and the features of finite tenses
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2015 Sequence-of-tense (SOT) is often described as a (past) tense verb form that does not correspond to a semantically interpretable tense. Since SOT clauses behave in other respects like finite clauses, the question arises as to whether the syntactic ...
Karen Zagona
doaj +1 more source
Suppletivismus als lexikographisches Problem (am Beispiel von allgemeinen einund zweisprachigen Wörterbüchern) [PDF]
Beiträge zur Allgemeinen und Vergleichenden Sprachwissenschaft, 2022 Suppletion is a linguistic phenomenon that is interesting from a linguistic-historical, linguistic-typological and foreign-language-didactic point of view because it concerns very frequently used lexemes.
Monika Bielińska
doaj +1 more source
Zu Kasusalternationen bei der Präposition na ‚auf‘ im Polnischen und ihren deutschen Entsprechungen [PDF]
Beiträge zur Allgemeinen und Vergleichenden Sprachwissenschaft, 2022 The article is dedicated to the local preposition na ‘on’ in Polish and its German equivalents auf. The main focus of the study are case alternations associated with the use of the preposition. The locative case in Polish is regarded as a structural case.
Anna Pilarski
doaj +1 more source
Biological and molecular characterization of P101 isolate, a tobamoviral pepper strain from Bulgaria
, 2021 A tobamovirus isolated from pepper crops in Bulgaria has been characterized, and is referred to below as P101. It was closely related to Paprika mild mottle virus (PaMMV) (Dutch isolate), based upon the serological relationship of its coat protein, and ...
Serra, María Teresa +6 more
core +1 more source