Results 11 to 20 of about 27,593 (112)

PI3 kinase signaling pathway in hematopoietic cancers: A glance in miRNA's role. [PDF]

open access: yesJ Clin Lab Anal, 2021
PI3K pathway involves in a wide verity of important biological events in cells such as proliferation, differentiation, apoptosis, and even drug resistance. It is confirmed that there is a relationship between dysregulation of mediators involved in this signaling pathway and different cancer types such as hematopoietic malignancies.
Roshandel E   +5 more
europepmc   +2 more sources

Immunomodulatory Mechanisms of Rehmanniae Radix Praeparata-Achyranthes Root-Chinese Angelica Root Combination in Nontraumatic Osteonecrosis of the Femoral Head: A Comprehensive Network Pharmacology and Molecular Docking Study Focusing on Immunological Pathways. [PDF]

open access: yesMediators Inflamm
Objective Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating condition characterised by immune dysregulation and sterile inflammation, which are increasingly acknowledged as central pathogenic mechanisms. This study aims to identify the core herbal combination for NONFH and systematically explore its immunomodulatory effects and ...
Li X   +10 more
europepmc   +2 more sources

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment. [PDF]

open access: yesMedComm (2020)
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Jiang M   +10 more
europepmc   +2 more sources

A Novel Construction of Substitution Box Involving Coset Diagram and a Bijective Map

open access: yesSecurity and Communication Networks, Volume 2017, Issue 1, 2017., 2017
The substitution box is a basic tool to convert the plaintext into an enciphered format. In this paper, we use coset diagram for the action of PSL(2,Z) on projective line over the finite field GF(29) to construct proposed S‐box. The vertices of the cost diagram are elements of GF(29) which can be represented by powers of α, where α is the root of ...
Abdul Razaq   +6 more
wiley   +1 more source

7th Drug hypersensitivity meeting: part two

open access: yesClinical and Translational Allergy, Volume 6, Issue S3, 25 August 2016., 2016
Table of contents Poster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101) P92 16 years of experience with proton pump inhibitors (PPIs) Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez‐Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna Martinez P93 Allergy evaluation of quinolone ...
Javier Dionicio Elera   +437 more
wiley   +1 more source

Atmena autoriams

open access: yesVerbum, 2015
...
Verbum 2014 Nr. 5
doaj   +1 more source

HIV Glasgow, 23–26 October 2022, Glasgow, UK / Virtual

open access: yes, 2022
Journal of the International AIDS Society, Volume 25, Issue S6, October 2022.
wiley   +1 more source

The TatC component of the twin‐arginine protein translocase functions as an obligate oligomer

open access: yesMolecular Microbiology, Volume 98, Issue 1, Page 111-129, October 2015., 2015
We have identified amino acid substitutions in the Escherichia coli TatC protein that block the function of the wild type TatC when the two proteins are co‐produced. We show that in the presence of a substrate protein two TatC wild type protomers come into close proximity, allowing a disulphide bond to form across position M205C.
François Cléon   +8 more
wiley   +1 more source

How Conceptual Are Semantic Maps?

open access: yesLinguistic Discovery, 2010
The question addressed in this paper is whether (and to what extent) a semantic map aimed at representing the multifunctionality of a given construction (or set of constructions) in discourse can be thought of as endowed with conceptual reality.
Andrea Sansò
doaj   +1 more source

ATMENA AUTORIAMS

open access: yesVerbum, 2016
...
Verbum 2016 Nr. 7
doaj   +1 more source

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