Results 231 to 240 of about 48,580 (292)

Dietary modulation of antimicrobial peptides (HAMP and LEAP2) in Chinook salmon (Oncorhynchus tshawytscha) fed a phytobiotic functional diet: Integrated genomic characterisation and tissue‐specific expression

Journal of Fish Biology, EarlyView.
Abstract Antimicrobial peptides (AMPs) are key components of the innate immune system in fish, providing rapid protection against microbial pathogens. Among these, the liver‐expressed antimicrobial peptides (LEAPs), comprising LEAP‐1 (hepcidin; HAMP) and LEAP‐2, play central roles in host defence and iron regulation.
Roberta Marcoli, Jane E. Symonds, Seumas P. Walker, Cesar Lopez, Mark A. Preece, Christopher Battershill, Steve Bird   +6 more
wiley   +1 more source

Comprehensive genomic analysis of five kindreds with multiple childhood leukemias: importance of individual functional analysis for rare ETV6 germline variants. [PDF]

Hum Cell
Yamada A, Nagasawa S, Nakagawa M, Kamimura S, Inoue N, Watanabe H, Takagi M, Koga Y, Keino D, Nakayama H, Yoshimura J, Doi K, Mitsui J, Tsuji S, Moritake H.   +14 more
europepmc   +1 more source

Understanding the Meaning of a Good Death for People Living With Parkinson's Disease: Qualitative Study

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Parkinson's disease is the second most common neurodegenerative disorder globally. Despite growing attention to palliative care in Parkinson's disease, little is known about what constitutes a “good death” from the perspective of people living with Parkinson's disease (PLwPD).
Leonardo Martins, Rasa Mikelyte, Ricardo Silva Carvalho, Henrique Ballalai Ferraz, Déborah Oliveira, Julia Maria Vanelli, Natália Rocha Tardelli, Fernanda Bono Fukushima, Edison Iglesias de Oliveira Vidal   +8 more
wiley   +1 more source

NF-κB Pathway Activation Mutations Linked to Failure of CpG-Stimulated Karyotyping in DLBCL. [PDF]

Int J Lab Hematol
Chen X, Yang C, Lang X, Chen H, Wang S, Li B, Xiao S.   +6 more
europepmc   +1 more source

Parent/Caregiver Perspectives on the Healthcare Decision‐Making Involvement of Young People With Intellectual Disability: A Qualitative Study

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Young people with intellectual disability often have complex healthcare needs. Parent/caregivers can enhance their child's involvement in healthcare decision‐making to improve treatment adherence and health outcomes. Healthcare decision‐making is embedded within health literacy skillsets, and for people with intellectual disability ...
Jessica Keeley, Zhenmei Yeap, Thomas Nevill, Rachel Skoss, Aasta Abbott, Sandra Thompson, Sophie Haywood, Rachel Collins, Katherine Langdon, Jenny Downs   +9 more
wiley   +1 more source

Nasal administration of Protollin enhances monocyte phagocytosis and decreases CD8⁺ T cell cytotoxicity in subjects with early Alzheimer's disease: a Phase 1 clinical trial. [PDF]

NPJ Aging
Kolypetri P, da Silva P, Francisco RS, Frenkel D, Cecere RR, Kiliaan PCJ, Montini F, Saxena S, Clementi WA, Liu X, Sun C, Bergmark RW, Singhal T, Saraceno TJ, Zimmermann J, Gale SA, Selkoe DJ, Chitnis T, Weiner HL.   +18 more
europepmc   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

Journal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó, Veronika Sigutova, Anna M. Schneider, Anna Hoerder‐Suabedissen, Zoltán Molnár   +4 more
wiley   +1 more source

The effect of visual scene on VEMP responses. [PDF]

Eur Arch Otorhinolaryngol
Öztürk ŞT, Satıcı S, Yeral C, Polat Z, Yılmaz O.   +4 more
europepmc   +1 more source

Staying in the Unknown: Avoidance of Genetic Testing in Families With Hereditary Cancer Syndromes—A Qualitative Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To explore the experiences and challenges associated with genetic testing decisions among untested individuals from hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) families. Design Qualitative descriptive study. Methods Semi‐structured telephone interviews were conducted between 2022 and 2024 with 56 untested at‐risk ...
Ronit G. Tsemach, Elizabeth E. Half, Hagit Baris‐Feldman, Anastasia Weis, Sharon Simchoni, Sue Kim, Maria C. Katapodi, Sivia Barnoy, Efrat Dagan   +8 more
wiley   +1 more source

Explaining "unexplained" chronic pain to adolescents: a qualitative study of methods and techniques among expert professionals. [PDF]

BMC Pediatr
Depost A, Lefèvre H, Truelle PE, Moro MR, Dugué S, Loisel A.   +5 more
europepmc   +1 more source