Results 151 to 160 of about 307,194 (254)

Neural correlates of response inhibition following cognitive behavioral therapy in obsessive-compulsive disorder: a randomized controlled EEG study. [PDF]

BMC Psychol
Çınaroğlu M, Ülker SV, Yılmazer E, Sayar GH.   +3 more
europepmc   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Correction: The Cefazolin Inoculum Effect: An Underappreciated Factor in MSSA Treatment Strategies

Infectious Diseases and Therapy
Prakhar Srivastava, Elizabeth Singleton, Taylor Morrisette, Andrew David Berti, Remo Lorenzo Ventresca, Emily Brassell, Lyuba Benin, Razieh Kebriaei   +7 more
doaj   +1 more source

Enfermedades desmielinizantes P3 (Pósteres)

Neurology Perspectives, 2023
doaj   +1 more source

Pain-Related Fear Modulates Attentional Bias for Threat Processing in Chronic Pain: An ERP Study. [PDF]

J Pain Res
Luo W, Xiao L, Huang Z, Li Y.
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Enfermedades cerebrovasculares P3 (Pósteres)

Neurology Perspectives, 2023
doaj   +1 more source

Catecholaminergic Contributions to Inhibitory Control Following Physical Fatigue: Behavioral and Neurophysiological Findings. [PDF]

Eur J Sport Sci
Arenales Arauz YL, Omejc N, Diaz MA, Habay J, Vanderborght B, De Pauw K, Roelands B, Marusic U.   +7 more
europepmc   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Encapsulated cell therapy for local anti-CTLA-4 delivery in cancer immunotherapy. [PDF]

iScience
Engel A, Vernet R, Charrier E, Urwyler M, Von Rohr O, Saingier V, Courtout F, Abukscem S, Bouvarel T, Lathuiliere A, Guillarme D, Mach N, Grogg J.   +12 more
europepmc   +1 more source