Results 31 to 40 of about 307,069 (251)

P3 Flap: Technique for Fingertip Reconstruction

Plastic and Reconstructive Surgery, Global Open, 2023
Summary:. Fingertip amputations represent an important spectrum of injuries, and most are avulsions or crush trauma. There is no consensus about one single standard treatment, and a wide number of techniques are available. The authors present the P3 flap
Giovanna Petrella, MD, Norman Della Rosa, MD, Roberto Adani, MD   +2 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

It takes two to tango: Preserving daptomycin efficacy against daptomycin-resistant MRSA using daptomycin-phage co-therapy

Microbiology Spectrum
Daptomycin (DAP) is a cyclic lipopeptide antibiotic that targets the cell membrane and is commonly used for the treatment of multidrug-resistant Staphylococcus aureus infections, especially methicillin-resistant strains (MRSA).
Casey L. Madison, Anja S. J. Steinert, Corrin E. Luedeke, Neeka Hajjafar, Prakhar Srivastava, Andrew D. Berti, Arnold S. Bayer, Razieh Kebriaei   +7 more
doaj   +1 more source

Nothing as Practical as a Good Theory? The Theoretical Basis of HIV Prevention Interventions for Young People in Sub-Saharan Africa: A Systematic Review

AIDS Research and Treatment, 2012
This paper assesses the extent to which HIV prevention interventions for young people in sub-Saharan Africa are grounded in theory and if theory-based interventions are more effective.
Kristien Michielsen, Matthew Chersich, Marleen Temmerman, Tessa Dooms, Ronan Van Rossem   +4 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Global Functional Connectivity at Rest Is Associated with Attention: An Arterial Spin Labeling Study

Brain Sciences, 2023
Neural markers of attention, including those frequently linked to the event-related potential P3 (P300) or P3b component, vary widely within and across participants.
Shichun Chen, Yakun Zhang, Zongpai Zhang, Tony D. Zhou, Wenna Duan, George Weinschenk, Wen-Ming Luh, Adam K. Anderson, Weiying Dai   +8 more
doaj   +1 more source

Receptor-Triggered Peptide Self-Assembly Enables Multivalent Recruitment of Endogenous Antibodies for Cancer Immunotherapy. [PDF]

Adv Sci (Weinh)
Receptor‐triggered supramolecular self‐assembly converts monovalent antibody‐recruiting molecules into multivalent platforms directly on cancer cell membranes. The resulting fibrillar assemblies present clustered haptens that efficiently recruit endogenous antibodies, enabling selective complement‐mediated immune killing of EGFR‐positive cancer cells ...
Wang Y, Wu X, Zhao C, Han H, Xie W, Yuan D, Shi J.   +6 more
europepmc   +2 more sources

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Clinical study of Fungal corneal ulcer [PDF]

Perspectives In Medical Research, 2018
Aims & Objectives: To study the mode of presentation, risk factors and clinical presentation of fungal corneal ulcer, investigations regarding the type of fungus and the statistics regarding the common type of fungi that involve the cornea. Materials
Shrikrishna Ingle1 ,Lahari Aitharaju2 ,Krishna Chaitanya P3
doaj