Results 191 to 200 of about 37,116 (209)

Tandem association of CLOCK:BMAL1 complexes on DNA enables recruitment of CBP/p300 through multivalent interactions

open access: yes
Sharma D   +14 more
europepmc   +1 more source

The p300/CBP family: integrating signals with transcription factors and chromatin

open access: closedTrends in Cell Biology, 1997
Studies on the mechanisms through which the oncogene products of DNA tumour viruses subvert the physiological processes that control cell proliferation have yielded many important insights into the mammalian cell cycle. In the case of the adenovirus E1a oncoprotein, a number of distinct protein domains are required for it to exert its growth-promoting ...
Noriko Shiama
openaire   +3 more sources

p300/CBP Acts as a Coactivator of the Cone–Rod Homeobox Transcription Factor

open access: closedBiochemical and Biophysical Research Communications, 2000
CRX (cone-rod homeobox) is shown to play an important role on the photoreceptor cell maturation and maintenance. However, little is known about the molecular mechanism how CRX potentiates transcription. Here, we investigated the effect of several coactivators (p300/CBP, SRC-1, TIF2, and AIB1) on the transactivation function of CRX.
Y, Yanagi   +4 more
openaire   +3 more sources

CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein.

open access: closedCancer research, 1997
The structurally related transcriptional coactivators p300 and CBP possess histone acetyltransferase activity and associate with P/CAF, which is also a histone acetyltransferase. CBP and p300 have properties of tumor suppressor proteins; their interaction with P/CAF is disrupted by the adenoviral E1A oncoprotein, and the genes encoding CBP and p300 are
D M, Scolnick   +7 more
openaire   +2 more sources

Faculty Opinions recommendation of P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2019
Aishwarya Prakash, Nidhi Sharma
openaire   +1 more source

Structural and Functional Insights into TAZ2‐mediated CBP/p300 Recruitment by the Melanogenic Transcription Factor MITF

open access: closed, 2020
Alexandra D. Brown   +5 more
openalex   +1 more source

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