Results 31 to 40 of about 37,116 (209)

Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function [PDF]

, 2002
This work was supported by grants from the NIH (R01CA86072 to R.G.P. and R01CA72038-01 to S.A.W.F.) and The Susan Komen Breast Cancer Foundation (to R.G.P.). R.T.H. and E.J. were supported by the Medical Research Council. Y.-G.Y.
Chang, Chawnshang, Fu, Maofu, Fuqua, Suzanne A W, Hay, Ronald Thomas, Hopp, Torsten, Jaffray, E, Janne, OA, Palvimo, Jorma J, Pestell, RG0, Sakamaki, Toshiyuki, Wang, Chenguang, Wang, Jian, Yeung, YG, Zhang, Xueping   +13 more
core   +1 more source

Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. [PDF]

, 2002
Signal transducer and activator of transcription 3 (STAT3) transcription factors are cytoplasmic proteins that induce gene activation in response to cytokine receptor stimulation.
D.M. Heery, F. Bienvenu, H. Gascan, O. Coqueret, S. Avril, S. Giraud   +5 more
core   +2 more sources

TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases [PDF]

, 2019
The cytokine transforming growth factor β (TGFβ) plays a crucial role in the induction of both epithelial-to-mesenchymal transition (EMT) program and fibro-cirrhotic process in the liver, where it contributes also to organ inflammation following several ...
Amicone, Laura, Battistelli, Cecilia, Bisceglia, Francesca, Marchetti, Alessandra, Montaldo, Claudia, Noce, Valeria, Strippoli, Raffaele, Tripodi, Marco, Zammataro, Agatino   +8 more
core   +1 more source

Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression.

PLoS ONE, 2013
Rod and cone photoreceptor neurons in the mammalian retina possess specialized cellular architecture and functional features for converting light to a neuronal signal.
Anne K Hennig, Guang-Hua Peng, Shiming Chen   +2 more
doaj   +1 more source

Genome-wide profiling of H3K56 acetylation and transcription factor binding sites in human adipocytes. [PDF]

PLoS ONE, 2011
The growing epidemic of obesity and metabolic diseases calls for a better understanding of adipocyte biology. The regulation of transcription in adipocytes is particularly important, as it is a target for several therapeutic approaches.
Kinyui Alice Lo, Mary K Bauchmann, Amy P Baumann, Christopher J Donahue, Mark A Thiede, Lisa S Hayes, Shelley Ann G des Etages, Ernest Fraenkel   +7 more
doaj   +1 more source

SOX9 Knockdown-Mediated FOXO3 Downregulation Confers Neuroprotection Against Ischemic Brain Injury

Frontiers in Cell and Developmental Biology, 2021
BackgroundEvidence exists uncovering that SRY-box transcription factor 9 (SOX9) plays a role in ischemic brain injury (IBI). Thus, the current study was conducted to elucidate the specific role of SOX9 and the mechanism by which SOX9 influenced IBI ...
Yiming Deng, Yiming Deng, Yiming Deng, Gaoting Ma, Gaoting Ma, Gaoting Ma, Feng Gao, Feng Gao, Feng Gao, Xuan Sun, Xuan Sun, Xuan Sun, Lian Liu, Lian Liu, Lian Liu, Dapeng Mo, Dapeng Mo, Dapeng Mo, Ning Ma, Ning Ma, Ning Ma, Ligang Song, Ligang Song, Ligang Song, Xiaochuan Huo, Xiaochuan Huo, Xiaochuan Huo, Hongwei He, Hongwei He, Hongwei He, Zhongrong Miao, Zhongrong Miao, Zhongrong Miao   +32 more
doaj   +1 more source

The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP [PDF]

, 2011
The homologous cellular coactivators p300 and CBP contain intrinsic lysine acetyl transferase (termed HAT) activity. This activity is responsible for acetylation of several sites on the histones as well as modification of transcription factors.
Akagi, Arany, Balasubramanyam, Bannister, Basbous, Bedford, Boyes, Brownell, Burge, Cavanagh, Cerchietti, Cereseto, Chakravarti, Chan, Chen, Clerc, Cohen, Cook, Das, De Guzman, Diana G. Wright, Dion, Elsheikh, Ferrari, Ferreon, Ferreon, Fritsche, Gartenhaus, Gaudray, Goncalves, Griffis, Gu, Hamamori, He, Hebbes, Hivin, Horwitz, Hublitz, Isabelle Lemasson, Iyer, Jean-Michel Mesnard, Jin, Kannian, Kasibhatla, Kasper, Korzus, Kouzarides, Kung, Kurdistani, Kwok, Kwok, Legge, Lemasson, Lemasson, Lemasson, Lemasson, Lemasson, Li, Macfarlan, Manuyakorn, Morin, Mosashvilli, Mullighan, Murata, Nelson, Nicholas Polakowski, O'Connor, Ogiwara, Ogryzko, Pasqualucci, Patel, Poiesz, Polakowski, Ponting, Puppin, Puri, Rasti, Reid, Rodriguez, Roelfsema, Sakaguchi, Satou, Satou, Schiltz, Scoggin, Seligson, Seligson, Seo, Shyu, Spange, Sterner, Takemoto, Tanaka, Tang, Teufel, Thebault, Thomas, Torsten Wurm, Van Orden, Wang, Wojciak, Yoshida, Zhang, Zhao, Zhao, Zhao, Zimmermann   +106 more
core   +6 more sources

Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis [PDF]

, 2007
Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of proneural basic helix-loop-helix (bHLH) factors ...
Anderson, David J., He, Fei, Li, Jia-Da, Ng, Kwan L., Sun, Yi E., Zhang, Chengkang, Zhou, Qun-Yong   +6 more
core   +1 more source

Vascular Growth in the Fetal Lung [PDF]

, 2011
The structure of the lung is truly remarkable. It is primarily composed of three branched tubular networks (the airway, pulmonary artery and vein, bronchial artery and vein) which supply blood and air to the site of gas exchange and which maintain ...
Land, Stephen
core   +4 more sources

Factors related to RNA polymerase II transcription are localized in interchromatin granule clusters of Panorpa communis oocytes.

Folia Histochemica et Cytobiologica, 2009
Diplotene oocyte nucleus of the scorpionfly Panorpa communis is transcriptionally silent and contains numerous nuclear bodies including interchromatin granule clusters (IGCs).
Vladimir Parfenov, Florina Batalova
doaj   +1 more source