Results 221 to 230 of about 71,455 (301)

Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila

The FEBS Journal, Volume 293, Issue 11, Page 3259-3273, June 2026.
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause, Marco Borsò, Marisa Müller, Axel Imhof, Zivkos Apostolou, Peter B. Becker   +5 more
wiley   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, Volume 293, Issue 12, Page 3528-3544, June 2026.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

Neural Foundations Supporting Prosocial Behaviors: A Scoping Review of EEG/ERP Evidence During Adolescence and Emerging Adulthood

Psychophysiology, Volume 63, Issue 6, June 2026.
ABSTRACT Adolescence is a particularly important period for prosocial development given the foundational changes that occur in social and reward neural systems. Despite the temporal and developmental advantages of electroencephalography (EEG), no studies have compiled and analyzed existing EEG evidence of adolescent prosocial development.
Rebecca Revilla, Cailee M. Nelson, Kate Flory, Sarah R. Edmunds, Abigail L. Hogan, Caitlin M. Hudac   +5 more
wiley   +1 more source

Partial body mass regain attenuates lipid utilization and alters the hepatic lipidome linked to HDL dysfunction during metabolic syndrome in male rats

Physiological Reports, Volume 14, Issue 12, June 2026.
Abstract Increases in body mass are associated with the development of metabolic dysfunction‐associated steatotic liver disease (MASLD). Caloric restriction (CR) is the primary non‐pharmacological defense against MASLD; however, poor CR maintenance induces partial body mass regain (PR), leading to MASLD progression.
Eira E. Jardines, Manuel A. Cornejo, John W. Newman, Oliver Fiehn, Akira Nishiyama, Rudy M. Ortiz   +5 more
wiley   +1 more source

P300/CBP inhibition with inobrodib in combination with gilteritinib and venetoclax targets leukemia stem cells in epigenetic mutant AML. [PDF]

Sci Adv
Goetz ML, Romer-Seibert JS, Versace AM, Kogan S, Jeurkar C, Bowman RL, Brooks N, Frese K, Meyer SE.   +8 more
europepmc   +1 more source

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source

Augmentative and Alternative Communication as an Ecological Window on Neglect-Related Spatial Asymmetry After Hemorrhagic Stroke: A Longitudinal Case Report. [PDF]

Brain Sci
Rifici C, De Luca R, Corallo F, Miceli S, Caliri S, Calderone A, Calapai R, Mirabile A, Pagano M, Quartarone A, Calabrò RS.   +10 more
europepmc   +1 more source

Assessing Cognitive Responses and Serum Vitamin B₁₂ Levels in Newly Diagnosed Type 2 Diabetes Mellitus Patients Treated With Metformin: A Prospective Study. [PDF]

Cureus
Wakode S, Gour R, Lokhande SL, Singhai A, Wakode A, Bharshankar R, Singh J, Sukumar MS.   +7 more
europepmc   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source