Results 1 to 10 of about 651,566 (203)

In the SARS-CoV-2 Pandora Pandemic: Can the Stance of Premorbid Intestinal Innate Immune System as Measured by Fecal Adnab-9 Binding of p87:Blood Ferritin, Yielding the FERAD Ratio, Predict COVID-19 Susceptibility and Survival in a Prospective Population Database? [PDF]

Int J Mol Sci, 2023
SARS-CoV-2 severity predictions are feasible, though individual susceptibility is not. The latter prediction allows for planning vaccination strategies and the quarantine of vulnerable targets.
Tobi M, Bluth MH, Rossi NF, Demian E, Talwar H, Tobi YY, Sochacki P, Levi E, Lawson M, McVicker B.   +9 more
europepmc   +2 more sources

Improvement of the Antibacterial Activity of Phage Lysin-Derived Peptide P87 through Maximization of Physicochemical Properties and Assessment of Its Therapeutic Potential. [PDF]

Antibiotics (Basel), 2022
Phage lysins are a promising alternative to common antibiotic chemotherapy. However, they have been regarded as less effective against Gram-negative pathogens unless engineered, e.g., by fusing them to antimicrobial peptides (AMPs).
Vázquez R, Doménech-Sánchez A, Ruiz S, Sempere J, Yuste J, Albertí S, García P.   +6 more
europepmc   +2 more sources

Monomodular Pseudomonas aeruginosa phage JG004 lysozyme (Pae87) contains a bacterial surface-active antimicrobial peptide-like region and a possible substrate-binding subdomain. [PDF]

Acta Crystallogr D Struct Biol, 2022
The structure of the monomodular Pseudomonas aeruginosa bacteriophage JG004 lysin Pae87 is presented and investigated in relation to repurposing its function as an antimicrobial agent. The structure with its peptidoglycan ligand revealed a possible cell‐wall‐binding region.
Vázquez R, Seoane-Blanco M, Rivero-Buceta V, Ruiz S, van Raaij MJ, García P.   +5 more
europepmc   +2 more sources

Semaphorin 3E-Plexin D1 Axis Drives Lung Fibrosis through ErbB2-Mediated Fibroblast Activation. [PDF]

Adv Sci (Weinh)
TGF‐β1 stimulation in fibroblasts leads to increased Furin expression, Furin‐mediated cleavage of P87‐Sema3E to P61‐Sema3E, which affects fibroblast function through the autocrine pathway, and the P61‐Sema3E‐PlexinD1 axis promotes fibroblast activation, proliferation and migration by affecting ErbB2 phosphorylation, which in turn activates the ErbB2 ...
Deng Z, Chen J, Yang R, Zhan Y, Chen S, Zhang J, Fu H, Gu Y, Huang Q, Wu J, Shan L, Gounni AS, Xie J.   +12 more
europepmc   +2 more sources

PENGGUNAAN MODEL PEMBELAJARAN KOOPERATIF TIPE TEAMS GAMES TOURNAMENT (TGT) TERHADAP HASIL BELAJAR PPKN PESERTA DIDIK KELAS X IPA 1 SMA NEGERI 3 PONTIANAK [PDF]

Satya Widya
Tujuan penelitian ini untuk menganalisis penerapan model pembelajaran kooperatif tipe Teams Games Tournament (TGT) terhadap hasil belajar peserta didik dengan menggunakan jenis Penelitian Tindakan Kelas (PTK).
Randi Saputra Randi
doaj   +3 more sources

Long-term effectiveness of benralizumab in severe eosinophilic asthma patients treated for 96-weeks: data from the ANANKE study

Respiratory Research, 2023
Background The efficacy of benralizumab has been broadly demonstrated in severe eosinophilic asthma (SEA), but only few real-life studies evaluated its long-term effects.
A. Vultaggio, M. Aliani, E. Altieri, P. Bracciale, L. Brussino, M. Caiaffa, P. Cameli, G. Canonica, C. Caruso, S. Centanni, M. D'Amato, F. De Michele, S. D. Del Giacco, F. Di Marco, F. Menzella, G. Pelaia, P. Rogliani, M. Romagnoli, Pietro Schino, G. Senna, Marco Benci, S. Boarino, J. Schroeder   +22 more
semanticscholar   +1 more source

96-Channel on-chip reconfigurable optical add-drop multiplexer for multidimensional multiplexing systems

Nanophotonics, 2022
The multi-dimensional multiplexing technology is very promising for further increasing the link capacity of optical interconnects. A 96-channel silicon-based on-chip reconfigurable optical add-drop multiplexer (ROADM) is proposed and demonstrated for the
Weike Zhao, Yingying Peng, Xiaoping Cao, Shi Zhao, Ruoran Liu, Yihui Wei, Dajian Liu, Xiaolin Yi, Sha-Sha Han, Yuanjian Wan, Kang Li, Guangze Wu, Jian Wang, Yaocheng Shi, D. Dai   +14 more
semanticscholar   +1 more source

Posttransplant cyclophosphamide for prevention of graft-versus-host disease: results of the prospective randomized HOVON-96 trial

Blood Advances, 2022
Key Points PT-Cy after NMA matched alloHSCT will increase the proportion of patients that survive without severe GVHD. PT-Cy could allow for implementation of early posttransplant chemo- and immunotherapy to further reduce the relapse risk after alloHSCT.
A. Broers, C. N. De Jong, K. Bakunina, M. Hazenberg, M. van Marwijk Kooy, M. D. de Groot, M. van Gelder, J. Kuball, B. van der Holt, E. Meijer, J. Cornelissen   +10 more
semanticscholar   +1 more source

Searching Information through Technology and Human Interaction [PDF]

, 2023
The Computer Age also known as Digital Age and Information Age and New Media Age has been the most impactable historical period of human civilization If well the truth that its precursor the Industrial Revolution drastically changed the way ...
Joel Laffita Rivera
core   +2 more sources

miR-96-5p targets PTEN to mediate sunitinib resistance in clear cell renal cell carcinoma

Scientific Reports, 2022
A multiple receptor tyrosine kinase inhibitor, sunitinib, is a first-line therapy for clear cell renal cell carcinoma (CCRCC). Unfortunately, it has the major challenges of low initial response rate and resistance after about one year of treatment.
Sang eun Park, Wonju Kim, Jialing Hong, D. Kang, Seulki Park, J. Suh, D. You, Yun‐Yong Park, N. Suh, J. Hwang, Choung-Soo Kim   +10 more
semanticscholar   +1 more source