Results 31 to 40 of about 653,419 (161)

Visual percepts evoked with an Intracortical 96-channel microelectrode array inserted in human occipital cortex.

open access: yesJournal of Clinical Investigation, 2021
BACKGROUND A long-held dream of scientists is to transfer information directly to the visual cortex of blind individuals, thereby restoring a rudimentary form of sight. However, no clinically available cortical visual prosthesis yet exists.
E. Fernández   +13 more
semanticscholar   +1 more source

The Coverage of Events After Maidan Protests and the Annexation of Crimea in Local Russian-Language Newspapers in Lithuania (March, 2014)

open access: yesInformacijos Mokslai, 2020
In 2014, some significant geopolitical changes in the region of Central and Eastern Europe took place. After the so-called Euromaidan events in Ukraine, Moscow took advantage of the situation and annexed the Crimean peninsula.
Viktor Denisenko
doaj   +1 more source

Recent progress in thermosensitive hydrogels and their applications in drug delivery area

open access: yesMedComm – Biomaterials and Applications, Volume 2, Issue 3, September 2023., 2023
Review Paper highlighted the background of thermosensitive hydrogels, their properties, and their applications in transdermal, oral, ophthalmic, intravaginal, nasal, rectal, cancer therapy, and cell‐loaded drug delivery systems as shown in the preview.
Bangul Khan   +10 more
wiley   +1 more source

What is the usage of the Brisbane Evidence Based Language Test in clinical practice?: A speech language therapy survey

open access: yesInternational Journal of Language &Communication Disorders, Volume 58, Issue 4, Page 1113-1132, July/August 2023., 2023
Abstract Background A number of practice barriers (e.g., time constraints, patient comorbidities and competing demands) exist as regards the evidence‐based assessment of adult language within the acute hospital setting. There is need for an evidence‐based, diagnostically validated, adaptable, comprehensive and efficient aphasia assessment. The Brisbane
Rhiannon Hounslow   +2 more
wiley   +1 more source

Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis

open access: yesEuropean Respiratory Journal, 2021
Drug susceptibility testing of M. tuberculosis is rooted in a binary susceptible/resistant paradigm. While there are considerable advantages in measuring the minimum inhibitory concentrations (MICs) of a panel of drugs for an isolate, it is necessary to ...
P. Fowler
semanticscholar   +1 more source

RAS‐targeted cancer therapy: Advances in drugging specific mutations

open access: yesMedComm, Volume 4, Issue 3, June 2023., 2023
Personalized therapeutic strategy targeting specific mut‐RAS‐induced cancers is essential. Cancer type, RAS mutation type, activation of downstream pathways, and clinicopathological background should be comprehensively considered when designing strategies for drug combinations.
Cen Liu   +7 more
wiley   +1 more source

Week 96 extension results of a Phase 3 study evaluating long-acting cabotegravir with rilpivirine for HIV-1 treatment

open access: yesAIDS (London), 2021
Supplemental Digital Content is available in the text Background: ATLAS (NCT02951052), a phase 3, multicenter, open-label study, demonstrated that switching to injectable cabotegravir (CAB) with rilpivirine (RPV) long-acting dosed every 4 weeks was ...
S. Swindells   +20 more
semanticscholar   +1 more source

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

open access: yesMedicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023
Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman   +6 more
wiley   +1 more source

RETHINKING Science Communication Education and Training: Towards a Competence Model for Science Communication

open access: yesFrontiers in Communication, 2021
Science communication is at a pivotal stage in its development due to the emergence of digital communication platforms that are not only presenting new opportunities but are also leading to new challenges.
Birte Fähnrich   +5 more
doaj   +1 more source

Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission and function in isolated skeletal muscle

open access: yesBritish Journal of Pharmacology, Volume 179, Issue 24, Page 5273-5289, December 2022., 2022
Background and Purpose Donepezil, a piperidine inhibitor of acetylcholinesterase (AChE) prescribed for treatment of Alzheimer's disease, has adverse neuromuscular effects in humans, including requirement for higher concentrations of non‐depolarising neuromuscular blockers during surgery.
Robert R. Redman   +4 more
wiley   +1 more source

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