Results 41 to 50 of about 1,463,960 (261)

Some Carleman-type inequalities in ( p , q ) $(p,q)$ -calculus

open access: yesJournal of Inequalities and Applications
In this paper, we construct ( p , q ) $\left (p,q\right )$ -type Jessen’s inequality using the properties of convex functions. On this basis, we generalize the classical Carleman integral-type inequality in ( p , q ) $\left (p,q\right )$ -calculus and ...
Jiao Yu, Lin Han
doaj   +1 more source

Existence of a mountain pass solution for a nonlocal fractional ( p , q ) $(p, q)$ -Laplacian problem

open access: yesBoundary Value Problems, 2020
Here, a nonlocal nonlinear operator known as the fractional ( p , q ) $(p,q)$ -Laplacian is considered. The existence of a mountain pass solution is proved via critical point theory and variational methods.
F. Behboudi, A. Razani, M. Oveisiha
doaj   +1 more source

Some approximation results on Bleimann-Butzer-Hahn operators defined by (p,q)-integers

open access: yesFilomat, 2016
In this paper we introduce a generalization of the Bleimann-Butzer-Hahn operators based on (p,q)-integers and obtain Korovkin?s type approximation theorem for these operators. Furthermore, we compute convergence of these operators by using the modulus of continuity.
Mursaleen, M.   +3 more
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A de Casteljau Algorithm for Bernstein type Polynomials based on (p,q)-integers

open access: yes, 2015
16 pages, 7 figures, basis function revised.
Khan, Khalid   +2 more
openaire   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

On the convergence of Lupaş (p,q) $(p,q)$-Bernstein operators via contraction principle

open access: yesJournal of Inequalities and Applications, 2019
The present paper deals with the limit behavior of iterates of Lupaş q- and (p,q) $(p,q)$-Bernstein operators. We obtain the convergence for Lupaş q- and (p,q) $(p,q)$-Bernstein operators by using the contraction principle.
Haifa Bin Jebreen   +2 more
doaj   +1 more source

Some approximation properties of new ( p , q ) $( p,q ) $ -analogue of Balázs–Szabados operators

open access: yesJournal of Inequalities and Applications, 2021
In this paper, a new ( p , q ) $( p,q ) $ -analogue of the Balázs–Szabados operators is defined. Moments up to the fourth order are calculated, and second order and fourth order central moments are estimated.
Hayatem Hamal, Pembe Sabancigil
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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