Results 171 to 180 of about 24,223,577 (290)

The Preparation of Novel Fluorenes Inspired by Hipposudoric Acid

open access: yesHelvetica Chimica Acta, EarlyView.
In this research we report on the design and synthesis of a series of fluorene‐based derivatives loosely inspired by the tricyclic framework of hipposudoric acid. Preparation of sixteen novel N‐alkylated derivatives was accomplished via a series of concise one‐step amide N‐alkylation reactions.
Munib Uddin   +3 more
wiley   +1 more source

Development of innovative therapies for multiresistant bacteria treatment: new application for a clinically sperimental molecule as inhibitor for Pseudomonas aeruginosa Quorum sensing

open access: yes
reservedPseudomonas aeruginosa è un batterio Gram-negativo che presenta molteplici resistenze agli antibiotici di uso comune. Una nuova strategia per eradicare il batterio è agire sul Quorum Sensing (QS), che rappresenta il meccanismo attraverso cui ...
GUERRA, GIULIA
core  

Prevalence of Multidrug‐Resistant Bacteria on Hospital Face Masks: A Surveillance Report

open access: yesiLABMED, EarlyView.
Hospital masks can harbor Klebsiella michiganensis for at least 24 h after disposal. This enteric bacterium poses a risk to immunocompromised patients and highlights the need for improved mask decontamination protocols to prevent hospital‐associated infections.
Shilpa Malakar   +4 more
wiley   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

open access: yesInterdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li   +15 more
wiley   +1 more source

Factors associated with discharge on higher respiratory support for children with tracheostomy hospitalized with bacterial tracheostomy‐associated infections: A prospective, multicenter cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract We conducted a multicenter prospective cohort study to identify factors associated with discharge on higher respiratory support in children with tracheostomy hospitalized for bacterial tracheostomy‐associated infections (bTRAINs). We included children 0–21 years with tracheostomy hospitalized for bTRAIN at six freestanding children's hospitals
Krystal S. Jin   +13 more
wiley   +1 more source

Gas chromatography–mass spectrometry analysis and comprehensive evaluation of antibacterial, antioxidant and anti‐inflammatory properties of Thymus capitatus extracts from Libya

open access: yesJSFA reports, EarlyView.
Abstract Background The emergence of multidrug‐resistant bacteria necessitates the development of alternative therapeutic approaches. Thymus capitatus, a Mediterranean medicinal plant, has been traditionally used to treat various ailments, but its bioactive potential from Libyan origins remains underexplored.
Ahmed Saeed Kabbashi   +9 more
wiley   +1 more source

Patient-Specific Coculture of S. aureus and P. aeruginosa Enhances Epithelial Barrier Disruption and Virulence in CRS. [PDF]

open access: yesInt Forum Allergy Rhinol
MMed XS   +6 more
europepmc   +1 more source

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