A Pseudomonas aeruginosa-Derived Particulate Vaccine Protects against P. aeruginosa Infection [PDF]
Vaccines, 2021 Despite numerous efforts to develop an effective vaccine against Pseudomonas aeruginosa, no vaccine has yet been approved for human use. This study investigates the utility of the P. aeruginosa inherently produced polyhydroxyalkanaote (PHA) inclusions and associated host–cell proteins (HCP) as a particulate vaccine platform.
Zennia Jean C. Gonzaga +4 more
openaire +5 more sources
Nanotubes Formation in P. aeruginosa
Cells, 2022 The present study discusses a biofilm-positive P. aeruginosa isolate that survives at pH levels ranging from 4.0 to 9.0. The biofilm consortia were colonized with different phenotypes i.e., planktonic, slow-growing and metabolically inactive small colony
Faraz Ahmed +10 more
doaj +3 more sources
Designing P. aeruginosa synthetic phages with reduced genomes [PDF]
Scientific Reports, 2021 In the era where antibiotic resistance is considered one of the major worldwide concerns, bacteriophages have emerged as a promising therapeutic approach to deal with this problem.
Diana P. Pires +5 more
doaj +5 more sources
Pseudomonas aeruginosa can be detected in a polymicrobial competition model using impedance spectroscopy with a novel biosensor [PDF]
, 2014 Electrochemical Impedance Spectroscopy (EIS) is a powerful technique that can be used to elicit information about an electrode interface. In this article, we highlight six principal processes by which the presence of microorganisms can affect impedance ...
Tucker, Nicholas P +10 more
core +5 more sources
Swarming of P. aeruginosa: Through the lens of biophysics. [PDF]
Biophys Rev (Melville), 2023 Swarming is a collective flagella-dependent movement of bacteria across a surface that is observed across many species of bacteria. Due to the prevalence and diversity of this motility modality, multiple models of swarming have been proposed, but a consensus on a general mechanism for swarming is still lacking. Here, we focus on swarming by Pseudomonas
Bru JL +4 more
europepmc +5 more sources
In-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs [PDF]
, 2011 Pseudomonas aeruginosa is a threatening, opportunistic pathogen causing disease in immunocompromised individuals. The hallmark of P. aeruginosa virulence is its multi-factorial and combinatorial nature.
Justyna Glik +35 more
core +2 more sources
Quorum Sensing Inhibitors to Quench P. aeruginosa Pathogenicity [PDF]
Pharmaceuticals, 2021 The emergence and the dissemination of multidrug-resistant bacteria constitute a major public health issue. Among incriminated Gram-negative bacteria, Pseudomonas aeruginosa has been designated by the WHO as a critical priority threat. During the infection process, this pathogen secretes various virulence factors in order to adhere and colonize host ...
Marine Duplantier +2 more
openaire +3 more sources
Structural and functional characterization of Pseudomonas aeruginosa CupB chaperones [PDF]
, 2010 Pseudomonas aeruginosa, an important human pathogen, is estimated to be responsible for,10% of nosocomial infections worldwide. The pathogenesis of P. aeruginosa starts from its colonization in the damaged tissue or medical devices (e. g.
Filloux, A. +23 more
core +1 more source
A laminar flow model of aerosol survival of epidemic and non-epidemic strains of Pseudomonas aeruginosa isolated from people with cystic fibrosis [PDF]
, 2008 YesCystic fibrosis (CF) is an inherited multi-system disorder characterised by chronic airway infection with pathogens such as Pseudomonas aeruginosa. Acquisition of P.
Daniel G Peckham +20 more
core +1 more source
The Iraqi Journal of Veterinary Medicine, 2014 To study the influence of whole sonicated Pseudomonas aeruginosa antigens (WSPAgs) on experimental arthritis induced by this bacteria, 15 rabbits were divided into 3 equal groups. The 1st group was inoculated intraarticular with 0.2 ml of p.
Ahmed Q. Al-Awadi
doaj +1 more source