Results 71 to 80 of about 25,979 (261)

16S/18S metabarcoding versus culture for aetiological assessment in infectious keratitis: A prospective paired‐sample study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Infectious keratitis (IK) is a vision‐threatening condition with diverse microbial aetiologies, yet conventional culture‐based diagnostics often have limited sensitivity. We investigated whether 16S/18S rRNA amplicon‐based next‐generation sequencing (NGS) can enhance aetiological assessment when used alongside standard microbiological ...
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Lise Kristensen, Anders Ivarsen   +6 more
wiley   +1 more source

Research progress on the potential mechanisms of Porphyromonas gingivalis in promoting Alzheimer’s disease [PDF]

口腔疾病防治
Alzheimer’s disease (AD), a common neurodegenerative disease, has been linked to periodontitis, especially Porphyromonas gingivalis (P. gingivalis) infection. This review summarizes the potential mechanisms and pathways through which P.
WANG Yujie, PENG Xian, LIAO Ga, ZHOU Xuedong
doaj   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source

Investigation of a viable but non-culturable state in Porphyromonas gingivalis and host cell invasion.

PLoS ONE
Porphyromonas gingivalis (P. gingivalis) is a gram-negative, black-pigmented, anaerobic pathogen known for its biofilm formation and its central role in periodontal disease. More recently, P. gingivalis has been implicated in various systemic conditions,
Adenrele Oludiran, Benjamin Lewis, Cole Pudwill, Sasanka Chukkapalli, Hanie Ahmadi, Daria Bannova, Alexander Linares, Jacob Burks, Jeffrey D Hillman, William A Dunn, Ann Progulske-Fox   +10 more
doaj   +1 more source

Transmembrane MUC1 assists oral microbial colonization in oral mucosa of potentially malignant disorders and oral squamous carcinoma

European Journal of Oral Sciences, EarlyView.
Abstract Transmembrane mucin 1 (tMUC1) provides oral mucosal barrier against pathogens. The invasion of oncopathogenic microbes can promote cancerous proliferation of cells via inflammatory responses, abnormal cellular signaling, angiogenesis, anti‐adhesion, and tumorigenesis.
Lauriina Soiniemi, Matias Kanniainen, Saga Ramsay, Arja Kullaa, Bina Kashyap   +4 more
wiley   +1 more source

Quorum sensing in Porphyromonas gingivalis and oral microbial interactions: a scoping review

Frontiers in Oral Health
ObjectivePorphyromonas gingivalis, a major periodontal pathogen, interacts with other oral microbes through quorum sensing, enhancing its growth and virulence, which contributes to periodontitis.
Zelda Ziyi Zhao, Wenwen Shan, Lifeng Guo, Chun Hung Chu, Jing Zhang, Jing Zhang   +5 more
doaj   +1 more source

Periodontitis and Chronic Conditions in Older Adults: A Scoping Review and Evidence Map of Systematic Reviews

Gerodontology, EarlyView.
ABSTRACT Background Periodontitis is a prevalent chronic inflammatory condition that frequently co‐occurs with systemic chronic diseases. Although older adults experience a high burden of both periodontitis and chronic conditions, the extent to which age‐specific evidence has been synthesised remains unclear.
Manisha Tamrakar, Najith Amarasena, Kym Michelle McCormick, Liana Luzzi, Gloria Mejia   +4 more
wiley   +1 more source

Colonization by Porphyromonas gingivalis in cervical squamous cell carcinomas promotes metastasis through FimA/CD151/ITGB1 signaling

Journal of Translational Medicine
Background Cervicovaginal microbiota dysbiosis has been implicated in the progression of cervical cancer. Recent studies have reported an increased abundance of Porphyromonas species in the vaginal microbiota of cervical cancer patients.
Xiuting Huang, Yuan Zhuang, Rui Wang, Jing Qu, Yuanyang Tan, Liang Li, Wenjun Pan, Huilong Nie, Kefeng Li, Yujing Lin, Liutong Yi, Xiaoyu Feng, Huimin Lan, Guangxue Wang, Xiantao Zeng, Zhenqi Jiang, De-Yun Wang, Yongkang Qiao, Yan Yan   +18 more
doaj   +1 more source

Use of an Oral Health‐Related Quality of Life Instrument to Measure Unmet Dental Care Needs in Adults With Inherited Bleeding Disorders

Haemophilia, EarlyView.
ABSTRACT Introduction Preventive dental care is vital for individuals with bleeding disorders to reduce the need for potentially invasive procedures. Although dental care is a mandated function of U.S. federally supported hemophilia treatment centers (HTCs), access to dental care is widely variable.
Miguel A. Escobar, Megan M. Ullman, Joanna Larson, Michael M. Chan, Marisela Trujillo   +4 more
wiley   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source