Make and break the alarmone: regulation of (p)ppGpp synthetase/hydrolase enzymes in bacteria
FEMS Microbiology Reviews, 2019 Bacteria use dedicated mechanisms to respond adequately to fluctuating environments and to optimize their chances of survival in harsh conditions. One of the major stress responses used by virtually all bacteria relies on the sharp accumulation of an ...
Séverin Ronneau, Régis Hallez
semanticscholar +1 more source
Fatty acid synthesis in Escherichia coli and its applications towards the production of fatty acid based biofuels [PDF]
, 2014 The idea of renewable and regenerative resources has inspired research for more than a hundred years. Ideally, the only spent energy will replenish itself, like plant material, sunlight, thermal energy or wind.
Janßen, H. (Helge) +1 more
core +1 more source
Frontiers in Microbiology, 2018 Virulence expression in the enteroaggregative Escherichia coli strain 042 requires the transcriptional activator AggR. We show in this report that, as reported for other virulence factors, the nucleotide second messenger (p)ppGpp is needed for a high ...
Mário Hüttener +5 more
doaj +1 more source
Microbial Cell Factories / Evaluation of three industrial Escherichia coli strains in fed-batch cultivations during high-level SOD protein production [PDF]
, 2013 Background: In the biopharmaceutical industry, Escherichia coli (E. coli) strains are among the most frequently used bacterial hosts for producing recombinant proteins because they allow a simple process set-up and they are Food and Drug Administration ...
Bayer, Karl +4 more
core +2 more sources
GTP Dysregulation in Bacillus subtilis Cells Lacking (p)ppGpp Results in Phenotypic Amino Acid Auxotrophy and Failure To Adapt to Nutrient Downshift and Regulate Biosynthesis Genes [PDF]
, 2013 Allison Kriel +6 more
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Lowering GTP Level Increases Survival of Amino Acid Starvation but Slows Growth Rate for Bacillus subtilis Cells Lacking (p)ppGpp [PDF]
, 2014 Alycia N. Bittner +2 more
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Nucleic Acids Research, 2019 Understanding how bacteria coordinate gene expression with biomass growth to adapt to various stress conditions remains a grand challenge in biology. Stress response is often associated with dramatic accumulation of cellular guanosine tetra- or penta ...
Manlu Zhu, Xiongfeng Dai
semanticscholar +1 more source
Growth Phase and (p)ppGpp Control of IraD, a Regulator of RpoS Stability, in Escherichia coli [PDF]
, 2009 Houra Merrikh +2 more
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(p)ppGpp inhibits 70S ribosome formation in Staphylococcus aureus by impeding GTPase-ribosome interactions [PDF]
, 2021 Daniel J. Bennison +5 more
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