Results 161 to 170 of about 5,197,105 (317)

Existence of positive solutions for \(p(x)\)-Laplacian problems

Electronic Journal of Differential Equations, 2007
Summary: We consider the system of differential equations \[ \begin{alignedat}{2} -\Delta_{p(x)} u&=\lambda [g(x)a(u) + f(v)] &\quad&\text{in }\Omega,\\ -\Delta_{q(x)} v&=\lambda [g(x)b(v) + h(u)] &\quad&\text{in }\Omega,\\ u&=v= 0 &\quad&\text{on } \partial \Omega, \end{alignedat} \] where \(p(x) \in C^1(\mathbb{R}^N)\) is a radial symmetric function ...
Horieh Ghorbani, Ghasem A. Afrouzi
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The high-redshift Universe with the International X-ray Observatory [PDF]

, 2011
We discuss some of the main open issues related to the light-up and evolution of the first accreting sources powering high redshift luminous quasars. We discuss the perspectives of future deep X-ray surveys with the International X-ray Observatory and ...
RANALLI, PIERO, VIGNALI, CRISTIAN, Comastri A., Gilli R., BRUSA, MARCELLA, Civano F.   +5 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

On the sub-supersolution method for \(p(x)\)-Laplacian equations

Journal of Mathematical Analysis and Applications, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Trapped in Endosome PEGylated Ultra‐Small Iron Oxide Nanoparticles Enable Extraordinarily High MR Imaging Contrast for Hepatocellular Carcinomas

Advanced Science
The early diagnosis of hepatocellular carcinomas (HCCs) remains challenging in the clinic. Primovist‐enhanced magnetic resonance imaging (MRI) aids HCC diagnosis but loses sensitivity for tumors
Dandan Zhou, Shanshan Shan, Lei Chen, Cang Li, Hongzhao Wang, Kuan Lu, Jianxian Ge, Ning Wang, Mohammad Javad Afshari, Yaqin Zhang, Jianfeng Zeng, Mingyuan Gao   +11 more
doaj   +1 more source

\(p(x)\)-Laplacian equations satisfying Cerami condition

Journal of Mathematical Analysis and Applications, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Improvements to MOS CCD technology for future X-ray astronomy missions [PDF]

, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis is concerned with the development of MOS charge-coupled device (CCD) technology for future applications in X-ray astronomy.
Murray, Neil John
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