Results 101 to 110 of about 5,551 (138)

Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers. [PDF]

Brain Commun
Lyons HS, Hubbard JC, Thomas CN, Roberts JA, Mugo CW, Bellamy Plaice G, Grech O, Prosser S, Strom A, Lucas SJE, Downie LE, Gill JM, Mitchell JL, Sinclair AJ, Hill LJ, UK mTBI-Predict Consortium .   +15 more
europepmc   +1 more source

Connectometry reveals differing associations of cortisol and PACAP with dorsal cingulum microstructure in posttraumatic stress

Granger SJ, Jobson SA, Ravichandran C, Devignes Q, Akman E, Blackford JU, May V, Hammack SE, Carlezon WA, Ressler KJ, Rauch SL, Rosso IM.   +11 more
europepmc   +1 more source

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PACAP

2013
International ...
John P. Vu, Patrizia M. Germano, Joseph R. Pisegna   +2 more
  +8 more sources

PACAP hybrid: A new PACAP receptor antagonist

Life Sciences, 1997
The effects of pituitary adenylate cyclase activating polypeptide (PACAP) hybrid, a synthetic antagonist, was investigated on NIH/3T3 cells containing PACAP receptor (R) splice variants (SVs). PACAPhybrid inhibited 125I-PACAP-27 binding to NIH/3T3 cells stably expressing PACAP-R basic, SV-1, SV-2 or SV-3 with an IC50 of 1000 nM. PACAPhybrid antagonized
J R, Pisegna, J, Leyton, T, Coelho, T, Hida, S, Jakowlew, M, Birrer, M, Fridkin, I, Gozes, T W, Moody   +8 more
openaire   +2 more sources

C-Terminally shortened pituitary adenylate cyclase-activating peptides (PACAP) discriminate PACAP I, PACAP II-VIP1 and PACAP II-VIP2 recombinant receptors

Regulatory Peptides, 1996
Pituitary adenylate cyclase-activating polypeptide (PACAP) analogues were tested for their ability to occupy the recombinant selective PACAP receptors (PACAP type I receptors) and the non-selective PACAP-vasoactive intestinal polypeptide (VIP) receptors (PACAP type II, VIP1 and PACAP type II, VIP2 receptors), stably transfected and expressed in Chinese
Gourlet, Philippe, Vandermeers, André, Vandermeers-Piret, Marie-Claire, Rathe, Jean, De Neef, Philippe, Robberecht, Patrick   +5 more
openaire   +2 more sources

PACAP and Type I PACAP Receptors in Human Prostate Cancer Tissue

Annals of the New York Academy of Sciences, 2006
Abstract: We characterized the expression and localization of pituitary adenylate cyclase‐activating polypeptide (PACAP) and its specific type I receptor variants in prostatic, hyperplastic, and carcinomatous tissue collected from patients undergoing prostate biopsy and surgery for benign prostatic hyperplasia (BPH) and prostate cancer (PCa).
C. Moretti, C. Mammi, G. V. Frajese, Stefania Mariani, GNESSI, Lucio, M. Arizzi, F. Wannenes, G. Frajese   +7 more
openaire   +5 more sources

Dual effects of PACAP on guinea pig gallbladder muscle via PACAP-preferring and VIP/PACAP-preferring receptors

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1997
The aims of this study were to determine the effect and mechanism of action of pituitary adenylate cyclase-activating peptide (PACAP) on gallbladder muscle. Guinea pig gallbladder muscle strips were studied isometrically. In noncontracted muscle strips, PACAP-27 and PACAP-38 caused dose-dependent contractions, whereas vasoactive intestinal peptide ...
H P, Parkman, A P, Pagano, J P, Ryan
openaire   +2 more sources

PACAP and PACAP receptors in insulin producing tissues: localization and effects

Regulatory Peptides, 1998
We have studied the localization, receptor occupancy and potency of the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) in insulin-producing tissues. Immunocytochemistry showed that PACAP-like immunoreactivity (PACAP-IR) was localized to pancreatic nerves with accumulation in intrapancreatic ganglia in both mouse and rat.
K, Filipsson, F, Sundler, J, Hannibal, B, Ahrén   +3 more
openaire   +2 more sources

PACAPs stimulate duodenal bicarbonate secretion at PACAP receptors in the rat

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1997
We investigated the effects of pituitary adenylate cyclase-activating polypeptides (PACAPs) on gastroduodenal HCO(3)- secretion in anesthetized rats and characterized their effects by comparison with the effects of vasoactive intestinal polypeptide (VIP).
K, Takeuchi, K, Takehara, S, Kato, K, Yagi   +3 more
openaire   +2 more sources

PACAP is an Endogenous Protective Factor—Insights from PACAP-Deficient Mice

Journal of Molecular Neuroscience, 2012
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a widespread neuropeptide with a diverse array of biological functions. Not surprisingly, the lack of endogenous PACAP therefore results in a variety of abnormalities. One of the important effects of PACAP is its neuroprotective and general cytoprotective role.
D, Reglodi, P, Kiss, K, Szabadfi, T, Atlasz, R, Gabriel, G, Horvath, P, Szakaly, B, Sandor, A, Lubics, E, Laszlo, J, Farkas, A, Matkovits, R, Brubel, H, Hashimoto, A, Ferencz, A, Vincze, Z, Helyes, L, Welke, A, Lakatos, A, Tamas   +19 more
openaire   +3 more sources