Results 51 to 60 of about 5,551 (138)

Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice.

PLoS ONE, 2014
Accumulating evidence from human genetic studies implicates the pituitary adenylate cyclase-activating polypeptide (PACAP) gene as a risk factor for psychiatric disorders, including schizophrenia and stress-related diseases.
Keisuke Hazama, Atsuko Hayata-Takano, Kazuki Uetsuki, Atsushi Kasai, Naoki Encho, Norihito Shintani, Kazuki Nagayasu, Ryota Hashimoto, Dora Reglodi, Tsuyoshi Miyakawa, Takanobu Nakazawa, Akemichi Baba, Hitoshi Hashimoto   +12 more
doaj   +1 more source

Role of pituitary adenylate cyclase‐activating polypeptide in modulating hypothalamic‐pituitary system

Reproductive Medicine and Biology, 2018
Background Pituitary adenylate cyclase‐activating polypeptide (PACAP) is a multifunctional peptide that is isolated and identified from the ovine hypothalamus, whose effects and mechanisms have been elucidated in numerous studies.
Aki Oride, Haruhiko Kanasaki, Satoru Kyo
doaj   +1 more source

PACAP [PDF]

, 2019
Sarah L. Gray, Daemon L. Cline
openaire   +2 more sources

VPAC1 and VPAC2 receptors mediate tactile hindpaw hypersensitivity and carotid artery dilatation induced by PACAP38 in a migraine relevant mouse model

The Journal of Headache and Pain
Background Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide pivotal in migraine pathophysiology and is considered a promising new migraine drug target.
Song Guo, Rikke Holm Rasmussen, Anders Hay-Schmidt, Messoud Ashina, Ayodeji A. Asuni, Jeppe Møller Jensen, Anja Holm, Sabrina Prehn Lauritzen, Glenn Dorsam, Jens Hannibal, Birgitte Georg, David Møbjerg Kristensen, Jes Olesen, Sarah Louise Christensen   +13 more
doaj   +1 more source

Hippocampal PACAP signaling activation triggers a rapid antidepressant response

Military Medical Research
Background The development of ketamine-like rapid antidepressants holds promise for enhancing the therapeutic efficacy of depression, but the underlying cellular and molecular mechanisms remain unclear.
Hai-Lou Zhang, Yan Sun, Zhang-Jie Wu, Ying Yin, Rui-Yi Liu, Ji-Chun Zhang, Zhang-Jin Zhang, Suk-Yu Yau, Hao-Xin Wu, Ti-Fei Yuan, Li Zhang, Miroslav Adzic, Gang Chen   +12 more
doaj   +1 more source

Discovery that PACAP, a mammalian neuropeptide, activates plant immunity through chemical screening. [PDF]

Front Plant Sci
Dong G, Xu Y, Zhou L, Ye Y, He K.
europepmc   +1 more source

Moderate Exercise Stimulates PACAP-Mediated Neurogenesis in Rat Dentate Gyrus and Cerebellar Cortex. [PDF]

J Funct Morphol Kinesiol
Maugeri G, Di Bartolo S, Palmeri N, D'Amico AG, Brancato D, Federico C, D'Agata V, Musumeci G.   +7 more
europepmc   +1 more source

A chemogenetic approach for temporal and cell-specific activation of endogenous GPCRs in vivo. [PDF]

Proc Natl Acad Sci U S A
Shingles G, Pang Q, Weng J, Singer R, Babar W, Shen J, Vazquez-Rivera L, Chen Y, Li P, Wang W.   +9 more
europepmc   +1 more source

PACAP Alleviates Paclitaxel-Induced Peripheral Neuropathy by Targeting Oxidative Stress and Mitochondrial Damage via the PGC-1α Pathway. [PDF]

CNS Neurosci Ther
Mo R, Wang C, Hu H, Shi S, Cao D, Luo Z, Yang H, Zhai M, Sun W.   +8 more
europepmc   +1 more source

Exploring the Link Between PACAP Signalling and Hyaluronic Acid Production in Melanoma Progression. [PDF]

Int J Mol Sci
Hajdú T, Kovács P, Katona É, Nguyen MN, Vágó J, Fillér C, Zákány R, Emri G, Tóth G, Reglődi D, Juhász T.   +10 more
europepmc   +1 more source