Results 151 to 160 of about 19,907 (261)

The Danish Pacemaker and ICD Register: Review of Clinical and Research Potential. [PDF]

Clin Epidemiol
Frausing MHJP, Schmidt M, Jørgensen OD, Jakobsen FN, Mikkelsen F, Larsen JM, Larroudé CE, Philbert BT, Kristensen J, Bosselmann HS, Gnanaganesh M, Albertsen AE, Malczynski J, Christensen LS, Hintze U, Broedbaek J, Nielsen JC, Johansen JB.   +17 more
europepmc   +1 more source

Ventricular Synchrony in Targeted Right Ventricular Septal Pacing: A Prospective Paired Comparison to Apical Placement

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background/Objectives Right ventricular (RV) apical pacing, the standard pacing approach, often induces ventricular dyssynchrony, potentially impairing cardiac function. This study aims to investigate whether targeted RV septal pacing, guided by functional electrophysiological feedback during implantation, reduces ventricular dyssynchrony ...
Bianca Iulia Catrina, Mihai Octavian Negrea, Ciprian Tănăsescu, Florina Batar, Florin‐Leontin Lazar, Ioan Manitiu   +5 more
wiley   +1 more source

Leadless atrial versus transvenous pacing for sinus node dysfunction: 1-year outcomes from the leadless ARRIVE real-world study. [PDF]

Europace
Nilsson KR, Birgersdotter-Green U, Saleem-Talib S, Bettampadi D, Yang Z, Diaz JO, Gabriels JK, Schaller RD, Shukla HH, Kühne M, Biffi M, Hofer D, Paisey J, Nabutovsky Y, Garweg C.   +14 more
europepmc   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Cerebrovascular regulation during heat stress

Experimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Effective and potentially retrievable: will leadless pacemakers become gold standard for pause prevention pacing? [PDF]

Eur Heart J Suppl
Magnani S, Bucci MG, Alì H, Cappato R.
europepmc   +1 more source

Quantifying skin microvascular function responses to distinct forms of heat stress in humans using optical coherence tomography

Experimental Physiology, EarlyView.
Abstract Optical coherence tomography (OCT) enables visualization and quantification of the cutaneous microvasculature, yet no study has compared responses to distinct forms of heating in humans. We hypothesized that local skin heating (LH) would evoke larger responses in microvascular diameter, velocity, flow and density than passive whole‐body ...
Kristanti W. Wigati, Robert A. McLaughlin, Harrison T. Caddy, Howard H. Carter, Louise H. Naylor, Daniel J. Green   +5 more
wiley   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source