Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy [PDF]
iMetaPolypoidal choroidal vasculopathy (PCV) is a distinct variant of neovascular age‐related macular degeneration (AMD) and a major cause of vision loss in older adults, yet its pathogenesis remains poorly understood.
Xinyu Zhao +18 more
doaj +3 more sources
Two year outcomes of as needed brolucizumab therapy in exudative age related macular degeneration with or without pachychoroid phenotype [PDF]
Scientific ReportsBrolucizumab is a second-generation vascular endothelial growth factor (VEGF) inhibitor. To date, there have been no reports comparing treatment outcomes between exudative age-related macular degeneration with or without the pachychoroid phenotype using ...
Yoshiko Fukuda +4 more
doaj +3 more sources
Natural Course of Pachychoroid Pigment Epitheliopathy [PDF]
Ophthalmology Science, 2022 Purpose: To investigate the natural course of pachychoroid pigment epitheliopathy (PPE). Design: A retrospective cohort study. Subjects: From the Kyoto central serous chorioretinopathy (CSC) cohort consisting of 548 patients with CSC as of September 2020,
Masahiro Miyake +2 more
exaly +4 more sources
Pachychoroid Spectrum Disorders: An Updated Review [PDF]
Journal of Ophthalmic & Vision Research, 2023 Pachychoroid disease spectrum is a recent term that has been associated with an increasing number of phenotypes. This review discusses updated findings for each of the typical pachychoroid entities (central serous chorioretinopathy, pachychoroid pigment ...
Richard B. Brown +2 more
doaj +2 more sources
Patterns of Choroidal Configuration in Pachychoroid Spectrum Disease [PDF]
Ophthalmology ScienceObjective: To assess choroidal alterations across clinically defined pachychoroid entities using ultra-widefield OCT angiography (OCTA) and to compare them with controls without retinal disease.
Vesna Bosic, Dr med +3 more
doaj +2 more sources
Real-world functional and anatomical outcomes of intravitreal aflibercept 8 mg in treatment-naïve neovascular age-related macular degeneration: a phenotype-based analysis by pachychoroid and polypoidal lesion status [PDF]
International Journal of Retina and VitreousBackground To evaluate the short-term functional and anatomical outcomes of intravitreal aflibercept 8 mg in treatment-naïve neovascular age-related macular degeneration (nAMD), and to explore whether the early treatment response varied according to ...
Amiko Matsuyama +7 more
doaj +2 more sources
Comparison of Choroidal Vascular Index Measurements in Pachychoroid Pigment Epitheliopathy using Manual ImageJ-Based Niblack and Protocol-Standardized Otsu Thresholding [PDF]
Journal of Current OphthalmologyPurpose: To compare choroidal vascular index (CVI) measurements obtained using manual ImageJ-based Niblack thresholding and protocol-standardized Otsu thresholding in patients with pachychoroid pigment epitheliopathy (PPE), employing a full-length ...
Doğukan Cömerter
doaj +2 more sources
Ultra-Wide-Field Optical Coherence Tomography Assessment of Choroidal Parameters in Central Serous Chorioretinopathy [PDF]
DiagnosticsPurpose: To analyze choroidal thickness (CT) and choroidal volume (CV) using ultra-wide-field (UWF) spectral-domain optical coherence tomography (SD-OCT) in patients with central serous chorioretinopathy (CSC) and to assess their associations with ...
Maciej Gawęcki +7 more
doaj +2 more sources
Retinitis pigmentosa with acute central serous chorioretinopathy with pachychoroid phenotype
Indian Journal of Ophthalmology. Case Reports, 2023 We report a case of retinitis pigmentosa (RP) coexisting with acute central serous chorioretinopathy (CSCR) with pachychoroid phenotype. A 37-year-old male showed clinical features of RP in both eyes with acute CSCR in the right eye.
Nikita Goel +4 more
doaj +1 more source
Indian Journal of Ophthalmology. Case Reports, 2021 Pachychoroid disease spectrum includes central serous chorioretinopathy (CSR) and pachychoroid neovasculopathy (PNV). Pachychoroid phenotype is characterized by choroidal hyperpermeability, dilated choroidal vessels (pachyvessels), and focal or diffuse ...
Barun Garg +5 more
doaj +1 more source