Results 41 to 50 of about 35,646 (287)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Law in other contexts: stand bravely brothers! a report from the law wars [PDF]

open access: yes, 2008
This essay argues against the two pillars of current research on law and globalisation, from the perspective of legal theory and political philosophy: first, the distinction between ‘well-ordered’ and ‘not so well-ordered’ societies; second, the ...
Agamben   +39 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih   +40 more
wiley   +1 more source

La mediación femenina como forma de acción política

open access: yesE-Spania, 2015
Dans cet article, nous étudions les pratiques de médiation auxquelles des femmes liées aux milieux monarchiques eurent recours lors de conflits politiques, dans les royaumes ibériques de la période Trastamare.
Ángela Muñoz Fernández
doaj   +1 more source

Labour mobility and diaspora: An overview of Solomon Islands’ historical regulatory experience, 1850s-2013 [PDF]

open access: yes, 2014
With less than 4,500 of its population of around 600,000 living overseas in 2013, the Solomon Islands ranks 138th in the world for diaspora formation.
Bedford, Richard   +5 more
core   +1 more source

Agency and Empowerment in consumption in relation to a patriarchal bargain: the case of Nigerian immigrant women in the UK [PDF]

open access: yes, 2016
Purpose This research aims to explore how female immigrants use consumption to challenge and support their husband's position within the context of their patriarchal bargain.
Lindridge, Andrew M.   +2 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Una reina en la retaguardia: las intervenciones pacificadoras de Isabel la Católica en la guerra de sucesión

open access: yesE-Spania, 2015
Cet article examine certaines des actions de pacificatrices réalisées par la reine Isabelle au cours de la guerre de succession à la Couronne de Castille dans les premières années du dernier quart du XVe siècle.
María del Pilar Rábade Obradó
doaj   +1 more source

Trends in Dermatopolymyositis Mortality, 1999–2022: A Nationwide Population‐Based Study, United States

open access: yesArthritis Care &Research, EarlyView.
We report the national burden of dermatopolymyositis mortality over the past quarter century using the US national vital statistics data. Age‐standardized mortality rates for dermatopolymyositis decreased at an annual rate of 3.8% each year, which was higher than the annual percent decrease for deaths from all other causes.
Elizabeth Matz, Ram R. Singh
wiley   +1 more source

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