The impact of freeze-dried food on gut microbiota composition: a preliminary study. [PDF]
Katarzyna BS +14 more
europepmc +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Optimizing Gas Composition and Moisture Content for Preservation of Specific Metabolites of Cultivated Stinging Nettle (<i>Urtica dioica</i> L.) Leaves. [PDF]
Dujmović M +6 more
europepmc +1 more source
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
Effect of Natural Air Cooling and Vacuum Pre-cooling on Shelf Life of Cake
doaj +2 more sources
Agarose-Based Films Enriched With Ascorbic Acid for Inhibiting Enzymatic Browning and Extending the Shelf Life of Fresh-Cut Apples. [PDF]
Bayrak S, Ozdemir H.
europepmc +1 more source
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Effect of Different Vacuum Pre-cooling Treatment on the Quality of Chinese Little Greens
doaj +2 more sources
Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou +23 more
wiley +1 more source
Black bean protein isolate-gum Arabic coacervated citronellal microcapsules: Preparation, characterization, antibacterial activities, and application in strawberry preservation. [PDF]
Mao H +7 more
europepmc +1 more source

