Results 101 to 110 of about 4,522,723 (378)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
SICE Journal of Control, Measurement, and System IntegrationPacket loss during data transfer for bilateral control systems can cause serious problems, such that the slave device cannot perform the desired operation, and the operator cannot consider the status of the slave side via the master device.
Toshiyuki Nagata, Yuichi Sawada
doaj +1 more source
Review of Counter-Based Digester ACK's Effectiveness in MANET Packet Loss Prevention
, 2023 Mohd. Abdul Bari Afsha Nishat
openalex +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Impact of Packet Loss Rate on Quality of Compressed High Resolution Videos. [PDF]
Sensors (Basel), 2023 Bienik J +3 more
europepmc +1 more source
Delay-Energy lower bound on Two-Way Relay Wireless Network Coding [PDF]
, 2014 Network coding is a novel solution that significantly improve the throughput and energy consumed of wireless networks by mixing traffic flows through algebraic operations. In conventional network coding scheme, a packet has to wait for packets from other
Chen, Wei, Zeng, Hongyi
core
Asymptotic Approximations for TCP Compound
, 2016 In this paper, we derive an approximation for throughput of TCP Compound connections under random losses. Throughput expressions for TCP Compound under a deterministic loss model exist in the literature.
Poojary, Sudheer, Sharma, Vinod
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Robust Fusion Kalman Estimator of the Multi-Sensor Descriptor System with Multiple Types of Noises and Packet Loss. [PDF]
Sensors (Basel), 2023 Zheng J, Cui W, Sun S.
europepmc +1 more source