Results 41 to 50 of about 15,546 (255)

WSN data gathering algorithm based on compressive sensing and matrix completion technique

Tongxin xuebao, 2018
The unreliable links and packet losing are ubiquitous in WSN.The performance of data collection algorithm based on compressive sensing is sensitive to packet losing.Firstly,the relationship between packet loss rate and CS-based reconstruction precision ...
Ce ZHANG, Ou LI, Xin TONG, Yanping YANG
doaj   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Congestion Control and Packet Scheduling for Multipath Real Time Video Streaming

IEEE Access, 2019
Real time video traffic has stringent delay requirement and is bandwidth demanding when streaming over the internet. Single path transmission may provide unsatisfactory picture quality to users due to packet loss, jitter, and low bandwidth.
Songyang Zhang, Weimin Lei, Wei Zhang, Yunchong Guan, Hao Li   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Enhancing Localization of Mobile Robots in Distributed Sensor Environments for Reliable Proximity Service Applications

IEEE Access, 2019
Mobile robots can effectively coordinate information among sensor nodes in a distributed physical proximity. Accurately locating the mobile robots in such a distributed scenario is an essential requirement, such that the mobile robots can be instructed ...
Xingzhen Bai, Zhijing Zhang, Lu Liu, Xiaojun Zhai, John Panneerselvam, Leijiao Ge   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Dynamic Event-Triggered Control for Delayed Nonlinear Markov Jump Systems under Randomly Occurring DoS Attack and Packet Loss

Mathematics
This paper aims to address the exponential stability and stabilization problems for a class of delayed nonlinear Markov jump systems under randomly occurring Denial-of-Service (DoS) attacks and packet loss.
Haiyang Zhang, Huizhen Chen, Lianglin Xiong, Yi Zhang   +3 more
doaj   +1 more source

Fine-Grained Analysis of Packet Loss in MANETs

IEEE Access, 2017
Most existing trust-based security schemes for mobile ad-hoc networks (MANETs) consider packet loss an indicator of possible attacks by malicious nodes.
Muhammad Saleem Khan, Daniele Midi, Majid Iqbal Khan, Elisa Bertino   +3 more
doaj   +1 more source