Results 111 to 120 of about 1,002,043 (319)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Controle da antracnose e qualidade de mangas (Mangifera indica L.) cv. haden, após tratamento hidrotémico e armazenamento refrigerado em atmosfera modificada Control of anthracnose and quality of mangoes (Mangifera indica L.) cv. Haden, after hydrothermic treatment and storage under refrigeratio and in modified atmosphere

Ciência e Agrotecnologia, 2007
A antracnose é uma doença que causa grandes prejuízos a comercialização da manga (Mangifera indica L.) e o seu controle é importante para manter a qualidade do fruto.
Luciana Costa Lima, Mário Sérgio Carvalho Dias, Marcos Venícios de Castro, Pedro Martins Ribeiro Júnior, Enilson de Barros Silva   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Use of sodium glutamate in pickled green olive packing. Effect on the physic-chemical characteristics and flavour

Grasas y Aceites, 1996
The paper studies the effect of previous olive washings on the pH increase and combined acidity produced by the use of sodium glutamate, added to give anchovy flavour to the product. Influence on previous treatments and pasteurization on the organoleptic
L. Rejano Navarro, A. H. Sánchez Gómez
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Genome-wide analysis of local chromatin packing in Arabidopsis thaliana

Genome Research, 2015
The spatial arrangement of interphase chromosomes in the nucleus is important for gene expression and genome function in animals and in plants. The recently developed Hi-C technology is an efficacious method to investigate genome packing. Here we present
Congmao Wang, Chang Liu, D. Roqueiro, D. Grimm, R. Schwab, C. Becker, C. Lanz, D. Weigel   +7 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Model-Based Heuristic for Packing Soft Rotated Rectangles in an Optimized Convex Container with Prohibited Zones

Mathematics
Packing soft rectangular objects in an optimized convex container is considered. Each soft rectangle can be freely translated and rotated, has a fixed area, and its dimensions can vary in certain limits.
Oksana Melashenko, Tetyana Romanova, Igor Litvinchev, Carlos Gustavo Martínez Gomez, Rui Yang, Bingtao Sun   +5 more
doaj   +1 more source

Generalized selfish bin packing [PDF]

, 2012
Standard bin packing is the problem of partitioning a set of items with positive sizes no larger than 1 into a minimum number of subsets (called bins) each having a total size of at most 1. In bin packing games, an item has a positive weight, and given a
Dosa, Gyorgy, Epstein, Leah
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source