Results 141 to 150 of about 310,664 (317)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
IMMIGRATION, MEAT PACKING, AND TRADE: IMPLICATIONS FOR IOWA
The paper examines changes in employment and wage patterns, industrial restructuring, and foreign competition that affect opportunities of recent immigrants to the non-metropolitan Midwest, especially to Iowa.
Wallace HUFFMAN, John A. MIRANOWSKI
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
REGIONAL CLUSTERS AS A FORM OF TERRITORIAL ARRANGEMENT OF INDUSTRY
Russian Journal of Economics and Law, 2007 The article views the theoretical issues of regional cluster investigation as a form of territorial organization of production powers in the market economy.
R. V. Kashbraziyev, M. V. Panasyuk
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Joint design of twin-antenna assisted space-time multilevel sphere packing aided coded modulation
, 2006 A new multilevel coding (MLC) scheme invoking sphere packing (SP) modulation is proposed, where the SP arrangement is jointly designed with a space time block code (STBC) for the sake of attaining an additional space diversity gain.
Alamri, O., Tee, R.Y.S., Hanzo, L.
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Is It a Jungle Out There? Meat Packing, Immigrants, and Rural Communities
The shift of the U.S. meat packing industry from urban to rural areas has generated controversy regarding potential social and economic costs of meat packing plants on their host communities.
Orazem, Peter F. +2 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source