Results 51 to 60 of about 18,960 (248)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Свойство выпуклости взаимных мультифрактальных размерностей [PDF]
Проблемы анализа, 2010 В работе установлено свойство выпуклости взаимной мультифрактальной упаковочной размерности подмножества пересечения носителей вероятностных борелевских мер μ и v.
Светова Н. Ю.
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Sphere packings in Euclidean space with forbidden distances
Forum of Mathematics, SigmaIn this paper, we study the sphere packing problem in Euclidean space where we impose additional constraints on the separations of the center points. We prove that any sphere packing in dimension $48$ , with spheres of radii r, such that no two ...
Felipe Gonçalves, Guilherme Vedana
doaj +1 more source
An Effective Corner Increment-Based Algorithm for the Two-Dimensional Strip Packing Problem
IEEE Access, 2018 The 2-D strip packing problem is an NP-hard combinatorial optimization problem. Given a strip with fixed width and infinite height, the aim of strip packing is to pack a set of rectangles with known widths and heights into the strip such that the used ...
Zhen Chen, Jianli Chen
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Packing measures and dimensions on cartesian products [PDF]
Publicacions Matemàtiques, 2013 Packing measures and Hewitt-Stromberg measures on products of metric spaces are investigated. New product inequalities for packing and lower packing dimensions are esatblished and used to solve a problem of Hu and Taylor regarding packing dimension.
openaire +7 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Packing Multidimensional Spheres in an Optimized Hyperbolic Container
MathematicsThe problem of packing multidimensional spheres in a container defined by a hyperbolic surface is introduced. The objective is to minimize the height of the hyperbolic container under non-overlapping and containment conditions for the spheres ...
Yuriy Stoyan +6 more
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Use of genetic algorithms for solving problems of optimal cutting
ITM Web of Conferences, 2016 Cutting and packing problem is one of the most common optimization problem. Even a small space or material savings allow obtaining substantial advantages on an industrial scale. This paper proposes the genetic algorithm to solve this problem. It includes
Sergievskiy Maxim, Syroezhkin Sergey
doaj +1 more source