Results 111 to 120 of about 331,306 (335)

What is isostructurality? Questions on the definition

open access: yesIUCrJ
Investigation of isostructurality leads to a deeper understanding of close-packing principles and contributes to the ability of crystal engineering. A given packing motif may tolerate small molecular changes within a limit.
Petra Bombicz
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Upaya Perbaikan Kualitas Proses Packing Semen Untuk Menurunkan Jumlah Cacat Kantong Pecah dengan Metode Six Sigma DMAIC (Studi Kasus PT. Semen Gresik (Persero), tbk. Tuban-Jawa Timur) [PDF]

open access: yes, 2007
PT. Semen Gresik merupakan perusahaan yang memproduksi semen. Penurunan kualitas terjadi pada beberapa karakteristik kualitas kritis (CTQ) di bagian packing.
HANDAYANI, DIAH KUSUMA
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Helical close-packing of anisotropic tubes

open access: yesNew Journal of Physics
Helically close-packed states of filaments are common in natural and engineered material systems, ranging from nanoscopic biomolecules to macroscopic structural components.
Benjamin R Greenvall, Gregory M Grason
doaj   +1 more source

Work System Design in the Wallet Production Process Using the Full Time Equivalent (FTE) and Cardiovascular Load (CVL) Method

open access: yesJurnal Teknik Industri: Jurnal Hasil Penelitian dan Karya Ilmiah dalam Bidang Teknik Industri
UKM Gudang Dompet is a company that produces wallets. The number of orders will affect employee performance because the number of targets achieved will increase the workload for employees, causing fatigue.
Yoni Fajar Misbaghi, Boy Isma Putra
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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