Results 111 to 120 of about 325,035 (334)
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Are these crystals isostructural? Symmetry requirements, extent of difference, and likeness of supramolecular interactions [PDF]
Structural DynamicsThe intentional design of crystalline materials, the fine-tuning of physical and chemical properties by slight chemical alterations - crystal engineering - requires understanding of solid-state assembly including supramolecular interactions and ...
Petra Bombicz
doaj +1 more source
On the Support of Minimizers of Causal Variational Principles
, 2013 A class of causal variational principles on a compact manifold is introduced and analyzed both numerically and analytically. It is proved under general assumptions that the support of a minimizing measure is either completely timelike, or it is singular ...
Finster, Felix, Schiefeneder, Daniela
core +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Helical close-packing of anisotropic tubes
New Journal of PhysicsHelically close-packed states of filaments are common in natural and engineered material systems, ranging from nanoscopic biomolecules to macroscopic structural components.
Benjamin R Greenvall, Gregory M Grason
doaj +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Jurnal Teknik Industri: Jurnal Hasil Penelitian dan Karya Ilmiah dalam Bidang Teknik IndustriUKM Gudang Dompet is a company that produces wallets. The number of orders will affect employee performance because the number of targets achieved will increase the workload for employees, causing fatigue.
Yoni Fajar Misbaghi, Boy Isma Putra
doaj +1 more source
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source