Results 121 to 130 of about 331,594 (334)

Experimental observation of gapped shear waves and liquid-like to gas-like dynamical crossover in active granular matter

Communications Physics
Unlike crystalline solids, liquids lack long-range order, resulting in diffusive shear fluctuations rather than propagating waves. Simulations predict that liquids exhibit a k-gap in wave-vector space, where solid-like transverse waves reappear above ...
Cunyuan Jiang, Zihan Zheng, Yangrui Chen, Matteo Baggioli, Jie Zhang   +4 more
doaj   +1 more source

A φ-Contractivity and Associated Fractal Dimensions

Fractal and Fractional
In this paper, we extend the concept of dimension of sets to some general frameworks relative to a gauge function φ, where two simultaneous dimensions are introduced.
Nifeen H. Altaweel, Olayan Albalawi, Razan Albalawi   +2 more
doaj   +1 more source

Use of packing equipment efficiency as an estimate of the overall plant effectiveness and as a tool to improve financial results of a food-processing unit

Brazilian Journal of Food Technology, 2017
Although Overall Equipment Effectiveness – OEE has been proven a useful tool to measure the efficiency of a single piece of equipment in a food processing plant it is possible to expand its concept to assess the performance of a whole production line ...
José Boaventura Magalhães Rodrigues, Antonio Carlos Dantas Cabral   +1 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Development of organic-diffusive gradients in thin films technique for measuring freely dissolved concentrations of tetracyclines using a commercial SPE packing

, 2022
Xuhui Li, Gengjian Meng, Zhuobin Chang, Xinxin Lian, MA Jian-hua, Ruichao Guo, Yulong Wang   +6 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Anisotropic Mobilities with Different Packing Motifs of the Thin Films of Fused-Selenophenes Measuring from the Sclc Method

, 2022
HIMADRI SHEKHAR KARMAKAR, Sarasija Das, Chandan Kumar, Sanjio S. Zade   +3 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Rate of convergence: the packing and centered Hausdorff measures of totally disconnected self-similar sets [PDF]

, 2017
Marta Llorente, M. Eugenia Mera, Manuel Morán   +2 more
openalex   +1 more source