Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Measuring the Impact of Meat Packing and Processing Facilities in the Nonmetropolitan Midwest: A Difference-in-Differences Approach [PDF]
, 2005 Georgeanne M. Artz +5 more
openalex +1 more source
Measuring packing density and water demand of Portland cement and SCMs by the mixing energy method [PDF]
, 2023 Nicolle Talyta Arriagada Soto +4 more
openalex +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Dynamic Assessment of Oligopoly, Oligopsony Power, and Cost Efficiency using the New Empirical Industrial Organization in the U.S. Beef Packing Industry [PDF]
In this paper, the new empirical industrial organization approach with a dynamic model is simultaneously employed to measure the degree of oligopoly, oligopsony power, and cost efficiency in the U.S. beef packing industry.
Chung, Chanjin, Ji, In Bae
core +1 more source
On interpreting Patterson--Sullivan measures of geometrically finite\n groups as Hausdorff and packing measures [PDF]
, 2014 David Simmons
openalex +1 more source
Talking about torque: Measuring pack accessibility - A review [PDF]
, 2015 Vacuum lug closures are a simple, reliable and low-cost packaging option used for the protection and promotion of jams, pickles and sauces. Several surveys and anecdotal evidence suggest that packaging of this type can be notoriously difficult to open.
Yoxall, Alaster, Rowson, J.
openaire +1 more source
Dimension inequalities of multifractal Hausdorff measures and multifractal packing measures
MATHEMATICA SCANDINAVICA, 2000 Given a Borel probability measure \(\mu\) on \({\mathbb R}^n\), the core of multifractal analysis consists of computing the (Hausdorff) dimensional multifractal spectrum of \(\mu\), that is, \[ f_{\mu}(\alpha)=\text{ dim}\left\{x: \alpha_{\mu}(x):= \lim_{r\rightarrow 0}{\log\mu B(x,r)\over \log r}=\alpha\right\}, \] and then establishing whether the ...
openaire +3 more sources