Results 201 to 210 of about 331,594 (334)

Learning molecular traits of human pain disease via voltage-gated sodium channel structure renormalization. [PDF]

Comput Struct Biotechnol J
Xenakis MN, Lampert A.
europepmc   +1 more source

Universality of Packing Dimension Estimates for Spectral Measures of Quasiperiodic Operators: Monotone Potentials [PDF]

Netanel Levi
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Damage Control Surgery in Obstetrics and Gynecology: Abdomino-Pelvic Packing in Multimodal Hemorrhage Management. [PDF]

J Clin Med
Kostov S, Kornovski Y, Yordanov A, Slavchev S, Ivanova Y, Alkatout I, Watrowski R.   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Self-Induced Buckling in Hollow Microgels. [PDF]

ACS Nano
Rank L, Zaccarelli E.
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

The Use of Metal Oxides (Al₂O₃ and ZrO₂) and Supports (Glass and Kaolin) to Enhance DBD Plasma-Catalytic CO₂ Conversion. [PDF]

Materials (Basel)
Dorosz A, Zaraska K, Lewak M, Małolepszy A, Jaworski J, Moskal A.   +5 more
europepmc   +1 more source

On the Packing Functions of some Linear Sets of Lebesgue Measure Zero [PDF]

Austin Anderson, Steven B. Damelin
openalex   +1 more source

New measures for estimating surface complementarity and packing at protein–protein interfaces [PDF]

, 2010
Pralay Mitra, Debnath Pal
openalex   +1 more source