Results 161 to 170 of about 222,862 (245)

Investigating the mechanism of inositol against paclitaxel chemoresistance on triple-negative breast cancer by using 7T multiparametric MRI and mitochondrial changes. [PDF]

Breast Cancer Res
Xuan W, Li W, Ke L, Shen Y, Zhang X, Chen Y, Ye Z, Zhuang C, Xie S, Wu R, Lin Y.   +10 more
europepmc   +1 more source

Blood‐based biomarkers in soft tissue sarcoma: Implications for immune checkpoint inhibitor therapy

International Journal of Cancer, EarlyView.
Abstract Soft tissue sarcoma (STS) is a rare and heterogeneous cancer, comprising approximately 1% of all adult cancers and 7%–15% of all childhood cancers. In the advanced stages, chemotherapy remains the standard‐of‐care, but efficacy is limited, with a response rate of 15%–30%, and responses are often short‐lived, with median progression‐free ...
Brie‐Anne Mannah, John J. Park, Su Yin Lim   +2 more
wiley   +1 more source

Successful targeting of multidrug-resistant tumors with bispecific antibodies. [PDF]

MAbs
Briante R, Zhai Q, Mohanty S, Zhang P, O'Connor A, Misker H, Wang W, Tan C, Abuhay M, Morgan J, Theolis R, Ponath P, Arathoon R.   +12 more
europepmc   +1 more source

Apoptosis regulators of the Bcl‐2 family play a key role in chemoresistance of cholangiocarcinoma organoids

International Journal of Cancer, EarlyView.
What's New? Poor prognosis in cholangiocarcinoma (CCA) is attributed to late diagnosis and intrinsic chemoresistance. In particular, resistance mechanisms that suppress apoptosis limit the effectiveness of gemcitabine‐based regimens, which remain the standard treatment.
Wunan Mi, Gilles S. van Tienderen, Shaojun Shi, Amy Broeders, Kathryn Monfils, Henk P. Roest, Luc J. W. van der Laan, Monique M. A. Verstegen   +7 more
wiley   +1 more source

Leaving Nothing Behind: Expanding the Clinical Frontiers of Drug-Coated Balloon Angioplasty in Coronary Artery Disease. [PDF]

J Cardiovasc Dev Dis
Marchetta M, Sasso S, Paragliola V, Maffi V, Chiricolo G, Massaro G, Russo G, Benedetto D, Muscoli S, Colonna G, Mandurino-Mirizzi A, Cortese B, Sangiorgi GM, Andò G.   +13 more
europepmc   +1 more source

Mass cytometric detection of homologous recombination proficiency in circulating tumor cells to predict chemoresistance of metastatic breast cancer patients

International Journal of Cancer, EarlyView.
What's New? Circulating tumor cells can offer insights into treatment responses and metastatic recurrence, but current analysis methods are limited. Here, the authors tested a newly developed mass cytometry panel comprising biomarkers such as γH2AX and RAD51 in longitudinally monitored metastatic breast cancer patients.
Kathrin Niedermayer, Henning Schäffler, Georgios Vlachos, Sara Greco, Kerstin Pfister, Barbara Volz, Leonie Ott, Hans Neubauer, Bernhard Polzer, André Koch, Sabine Riethdorf, Tanja Fehm, Wolfgang Janni, Thomas W. P. Friedl, Brigitte Rack, Ellen Heitzer, Fabienne Schochter, Lisa Wiesmüller   +17 more
wiley   +1 more source

Onvansertib inhibits cell proliferation and increases sensitivity to paclitaxel in uterine serous cancer cells. [PDF]

Am J Cancer Res
Haag JG, Shen X, Sinha N, Chen S, Deng B, Zhang H, John C, Sun W, Emanuele M, Zhou C, Bae-Jump V.   +10 more
europepmc   +1 more source

The association between additional radiotherapy after systemic chemotherapy and the prognosis of stage FIGO 2018 IVB cervical cancer

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Systemic platinum‐based chemotherapy is the first‐line treatment of choice for metastatic cervical cancer. While subsequent radiotherapy after primary chemotherapy is a potential option, its benefit remains unclear. This multicenter retrospective study aimed to evaluate whether post‐chemotherapy radiotherapy improves the prognosis of
Ai Miyoshi, Fumiaki Isohashi, Makoto Fujii, Tadashi Iwamiya, Masahiko Takemura, Yoshikazu Nagase, Takeshi Yokoi, Emi Yoshioka, Kimihiko Ito, Eri Yamabe, Kanji Masuhara, Tomoko Tsujie, Tadashi Kimura, Michiko Kodama   +13 more
wiley   +1 more source

Effects of albumin-bound paclitaxel combined with Sophora subprostrate polysaccharide on inflammatory factors and immune function in breast cancer rats. [PDF]

Discov Oncol
Ding C, Li Z, Zheng Y, Li K, Yu W, Kong L, Zhang Z.   +6 more
europepmc   +1 more source

Diversity and Ecological Factors Influencing Medicinal Plant Use Among Ethnolinguistic Groups in the Philippines 21世纪菲律宾人类文化语言学族群药用植物多样性及其生态关联研究

Integrative Conservation, EarlyView.
Plant order‐level Sankey plot illustrating plant use of ethnolinguistic groups for key disease types based on organ systems and use. Each node represents the strength of its interaction or usage. ABSTRACT Many human populations rely on natural remedies for health and healing, with traditional medicinal plants playing a vital role in diverse ...
Krizler C. Tanalgo, Yalaira Plang, Kier C. Dela Cruz, Meriam M. Rubio, Bona Abigail Hilario‐Husain, Jeaneth Magelen V. Respicio, Asraf K. Lidasan, Sumaira S. Abdullah, Gerald Vince N. Fabrero, Renee Jane A. Ele, Sedra A. Murray, Yvonne V. Saliling, Radji A. Macatabon, Lothy F. Casim, Jamaica Delos Reyes, Angelo R. Agduma   +15 more
wiley   +1 more source