Results 171 to 180 of about 213,637 (257)

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang, Hong‐Cheng Wei, Lin Jiang, Yi‐Sen Shao   +3 more
wiley   +1 more source

Phenotype Switching From Delayed Cutaneous Reactions to Immediate Anaphylaxis Upon Rechallenge With Paclitaxel. [PDF]

Allergy Asthma Immunol Res
Seo HJ, Park SJ, Song WJ, Kwon HS, Cho YS, Kim TB.   +5 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Modeling ovarian cancer chemoresistance: establishment of murine ID8 sublines and elucidation of adaptive mechanisms. [PDF]

Front Oncol
Xie S, Luo S, Bi A, Shi L, Zhang Y, Yin F, Liu X.   +6 more
europepmc   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

ST6GAL1 promotes cancer stem-like cell-associated paclitaxel resistance through the EGFR-mTOR-SOX2/BMI1 axis in non-small cell lung cancer. [PDF]

Cancer Drug Resist
Yang Y, Liang B, Hong W, Lee SH, Tang D, Xie S, Qin C, Shen L, Sun Z, Yan X, Li H, Wang X, Hu X, Ye T, Zhang W, Xu W.   +15 more
europepmc   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Reply: Paclitaxel- versus limus-coated balloons in the treatment of ISR. [PDF]

AsiaIntervention
Sagris M.
europepmc   +1 more source

Spatially Aware Acquisition‐Independent Deep Learning for IVIM MRI Parameter Estimation in Patients With Esophageal Cancer

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Neural controlled differential equations (NCDEs) recently emerged as a robust deep learning approach for quantitative MRI parameter estimation. NCDEs offer flexibility to changes in acquisition protocols by modeling the signal evolution dynamics. However, NCDE implementations operate on a voxel‐by‐voxel basis and cannot exploit spatial
Daan Kuppens, Roman S. Oort, Sebastiano Barbieri, Stella Mook, Gert J. Meijer, Oliver J. Gurney‐Champion   +5 more
wiley   +1 more source

Beyond STMN1: stathmin-family control of microtubule dynamics and paclitaxel resistance in cancer. [PDF]

Front Oncol
Li H, Shi L, Wang Q, Han W.
europepmc   +1 more source