Results 161 to 170 of about 213,637 (257)

Liquid biopsy across cancers: Integrating circulating biomarkers, tumor biology, artificial intelligence, and clinical translation

Interdisciplinary Medicine, EarlyView.
Liquid biopsy uses non‐invasive sampling of blood or body fluids to isolate circulating analytes, including circulating tumor DNA, circulating tumor cells, extracellular vesicles, and RNA. These are analyzed using next‐generation sequencing, qPCR, and proteomics to inform cancer detection, monitoring, and characterization. Figure created with BioRender.
Jaswinder Singh, Manjeet Kumar, Kajal Kamra   +2 more
wiley   +1 more source

MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization. [PDF]

Oncol Lett
Wang SH, Yeh CH, Wu CW, Hsu CY, Tsai EM, Hung CM, Lin MW, Hsieh TH.   +7 more
europepmc   +1 more source

Chemotherapy After Resection of Pancreatic Ductal Adenocarcinoma: Impact of Different Regimens in a Real‐World Population

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction The PRODIGE 24/CCTG PA.6‐ trial has shown an overall survival (OS) up to 55 months in patients treated with (modified) 5‐fluorouracil, leucovorin, irinotecan and oxaliplatin ((m)FOLFIRINOX) chemotherapy after resection of pancreatic ductal adenocarcinoma (PDAC). The applicability of these results to a real‐world patient population
N. C. Biesma, G. A. Cirkel, N. Haj Mohammad, M. Los, R. C. Verdonk, I. Q. Molenaar, L. A. Daamen, H. C. van Santvoort   +7 more
wiley   +1 more source

Pathological Complete Response to Nab-Paclitaxel-Containing Neoadjuvant Regimens in Early Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Salama RAA, El-Tanani M, Rabbani SA, Patni M, Bhongade B, Babiker R, Satyam SM, Rangraze IR, Wali AF, Talath S, Abdalla OE.   +10 more
europepmc   +1 more source

Pembrolizumab‐Induced Subacute Cutaneous Lupus Erythematosus: A Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Subacute cutaneous lupus erythematosus (SCLE) is an increasingly recognized cutaneous immune‐related adverse event of immune checkpoint inhibitors. We report an 83‐year‐old woman who developed pruritic annular and polycyclic plaques 10 weeks after starting pembrolizumab for oropharyngeal squamous cell carcinoma.
Sebastiano Posenato, Alba Guglielmo, Lucia Mantovani, Aikaterini Kalpaktsoglou, Simone Cavaliere, Alessandro Borghi   +5 more
wiley   +1 more source

Analysis of outcomes of nab-paclitaxel compared to other taxanes in early breast cancer: A study revealing the critical role of calendar-time bias in real-world drug comparisons. [PDF]

Breast
Xiao J, Huang M, Yan C, Wang Z, Wang T.
europepmc   +1 more source

LINC01605 Predicts the Poor Prognosis of Non‐Small Cell Lung Cancer and Promotes Chemotherapy Resistance by Regulating miR‐7111‐5p/ELK1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Non‐small cell lung cancer (NSCLC) is characterized by high incidence, mortality, and poor patient prognosis, with chemotherapy resistance being a common challenge. This research intends to identify key molecules involved in NSCLC and elucidate the regulatory role of the LINC01605/miR‐7111‐5p/ELK1 axis in chemotherapy resistance. LINC01605 and
Fang Zhang, Zhi‐Liang Yang, Tian‐Tian Qin, Guo‐Jun Zhang, Xiang Li   +4 more
wiley   +1 more source

Risk Factors Influencing Efficacy and Prognosis Evaluation of Neoadjuvant Systemic Therapy in Triple‐Positive Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT To identify the determinants of the response to neoadjuvant systemic therapy (NST) in triple‐positive breast cancer (TPBC), we retrospectively enrolled 520 patients with human epidermal growth factor receptor 2 (HER2)‐positive breast cancer who were treated at The First Affiliated Hospital of Chongqing Medical University between January 2015 ...
Lin‐Rui Miao, Hao Liu, Hai‐Ying Yu, Jian Chen, Ming‐Yu Yang, Ya‐Lan Zhang, Gang Tu, Ling‐Feng Tang   +7 more
wiley   +1 more source

Bioactive components from Sinomenium acutum exhibit anti-inflammatory activity and sensitize cervical cancer cells to paclitaxel. [PDF]

Nat Prod Bioprospect
Wang X, Zhu C, Du X, Wang Q, Yu J.
europepmc   +1 more source

The Prognostic Value of EDRIC and Its Association With Radiation‐Induced Lymphopenia in Patients With Esophageal Cancer Undergoing Radical Radiotherapy: A Single‐Center Chinese Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the predictive value of the estimated dose of radiation to immune cells (EDRIC) in patients with esophageal cancer receiving radical radiotherapy. We retrospectively reviewed the data of patients with esophageal cancer who underwent definitive radiotherapy at our institution.
Yue Ke, Chen Yang, Yu‐Xing Li, Xiao‐Xiao Liu, Xiao Liu, Jia‐Min Gao, Hong‐Bing Ma   +6 more
wiley   +1 more source