Results 261 to 270 of about 308,418 (340)

A Comparison of a Drug Coated Balloon With Drug Eluting Stent Strategy for Treating Coronary Bifurcation Lesions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The treatment of coronary bifurcation lesions (CBL) remains complex and associated with a higher rate of long‐term adverse cardiovascular events due to anatomical and procedural complexity. Aims We compared procedural outcomes between a drug coated balloon (DCB) only approach and a 2nd generation drug eluting stent (DES) for ...
Natasha Corballis, Ioannis Merinopoulos, U. Bhalraam, Tharusha Gunawardena, Vasiliki Tsampasian, Rajkumar Natarajan, Upul Wickramarachchi, Mohamed Mohamed, Allan Clark, Mamas A. Mamas, Vassilios S. Vassiliou, Simon Eccleshall, SPARTAN‐Norfolk Consortium, Tim Gilbert, Clint Maart, Johannes Reinhold, Paul Richardson, Alisdair Ryding, Trevor Wistow, Chris Sawh, Sulfi Sreekumar   +20 more
wiley   +1 more source

Platinum-based neoadjuvant chemotherapy in triple-negative breast cancer: An updated systematic review and meta-analysis. [PDF]

Medicine (Baltimore)
Wu J, Yan X, Fang J, Peng L, Zhao X.
europepmc   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

The efficacy of premedication with 10 mg versus 20 mg of intravenous dexamethasone for prevention of paclitaxel hypersensitivity reaction in low-risk gynecologic cancer patients: a non-inferiority, randomized controlled mono-institutional trial. [PDF]

BMC Cancer
Sa-Ngiamphorn N, Suprasert P, Charoentum C.   +2 more
europepmc   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Comparison of efficacy and safety in two versus three cycles of neoadjuvant immunotherapy plus chemotherapy for esophageal squamous cell carcinoma. [PDF]

J Cardiothorac Surg
Ye G, Pan G, Zhu X, Liu H, Geng G, Jiang J.   +5 more
europepmc   +1 more source

Molecular Docking and Target‐Specific Binding Profiles of Benzosuberane‐Based Compounds

ChemMedChem, EarlyView.
Benzosuberane represents a promising scaffold in medicinal chemistry. Several benzosuberane‐based derivatives are described in this review as anticancer agents, including antivascular agents, DNA‐intercalators, receptor modulators and kinase inhibitors.
Michail A. Saragatsis, Gemma K. Kinsella, James F. Curtin, Tao Zhang   +3 more
wiley   +1 more source

Paclitaxel and Cephalomannine Synergistically Induce PANoptosis in Triple-Negative Breast Cancer Through Oxygen-Regulated Cell Death Pathways. [PDF]

Antioxidants (Basel)
Gao X, Chen K, Jia S, Li J, Zhang H, Wang Y, Xie W.   +6 more
europepmc   +1 more source

Recent Advances of In Situ Anticancer Nanomedicine from Enzyme‐Instructed Self‐Assembly

ChemNanoMat, EarlyView.
This review summarizes advances in enzymatic self‐assemblies for generating in situ anticancer nanomedicine over the past five years. It highlights the unique features of enzyme substrates for in situ anticancer nanomedicine by discussing the representative examples.
Linrui Zou, Meihui Yi, Bing Xu
wiley   +1 more source

Multicomponent Reaction-Enabled Semisynthesis of Taxanes Yields an Analogue with Reduced Chemotherapy-Induced Neuropathy. [PDF]

JACS Au
Fu X, Yang H, Li Y, Niu G, Ren J, Liu X, Li X, Li Y, Shu J, Guo W, Liu T, Cai S, Shi T, Hu W.   +13 more
europepmc   +1 more source