Abnormal spindle‐like microcephaly‐associated protein helps radiotherapy resistant cells to evade spindle checkpoint surveillance and complete cell division after irradiation through destruction of microtubule stability, with subsequent increases in chromosome mis‐segregation and deteriorating chromosomal stability during mitosis to promote ...
Tao Zhong+13 more
wiley +1 more source
The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients. [PDF]
Simonsen E+7 more
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Application of Bryophytes to Foods, Food Additives and Phytomedicines
Little attention has been paid to the bryophytes for use in the human diet, despite the presence of 23,000 species worldwide. (Marchantia polymorpha). ABSTRACT Little attention has been paid to the bryophytes for application on the human diet, despite the presence of 23,000 species worldwide.
Yoshinori Asakawa, Jianbo Xiao
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Immune Checkpoint Inhibitors in Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor-Resistant Chemotherapy-Naïve Advanced Non-Small Cell Lung Cancer: A Meta-Analysis Based on Eight Randomized Trials. [PDF]
Huang L, Zhang S, Sun L, Ma J, Han C.
europepmc +1 more source
Advancements in Identification of Low‐Molecular‐Weight Peptides in Food Protein Hydrolysates
During the sample processing stage, sample collection, extraction and purification are carried out first to ensure the accuracy of the experimental data. Then, multi‐dimensional techniques such as mass spectrometry and chromatography are employed for in‐depth analysis of the samples.
Zhihui Chang+4 more
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GFPT2 promotes paclitaxel resistance in epithelial ovarian cancer cells via activating NF-κB signaling pathway. [PDF]
Xu ZJ, Liu B, Li RN, Linghu H.
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ABSTRACT Background Adenoid cystic carcinoma (ACC) is the second most common and treatment‐resistant salivary gland carcinoma (SGC). Although platinum‐based therapies are effective, the efficacy of eribulin, a microtubule inhibitor with an 18% response rate in a Phase II trial involving recurrent/metastatic SGC, in patients with advanced ACC after ...
Tomomi Sanomachi+16 more
wiley +1 more source
Correction to: Paclitaxel-coated balloon angioplasty vs. drug-eluting stenting for the treatment of coronary in-stent restenosis: a comprehensive, collaborative, individual patient data meta-analysis of 10 randomized clinical trials (DAEDALUS study). [PDF]
europepmc +1 more source
Inhibiting microtubule polymerization with EAPB02303, a prodrug activated by catechol-O-methyl transferase, enhances paclitaxel effect in pancreatic cancer models. [PDF]
Bigot K+19 more
europepmc +1 more source