Results 191 to 200 of about 25,932 (263)

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

open access: yesInternational Journal of Cancer, EarlyView.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel   +26 more
wiley   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

open access: yesInternational Journal of Cancer, EarlyView.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens   +14 more
wiley   +1 more source

Resource‐Adapted Triage Strategies for Women Testing HPV Positive With Self‐Collected Vaginal Samples in Cameroon

open access: yesInternational Journal of Cancer, EarlyView.
Although human papillomavirus (HPV) testing is recommended for cervical cancer screening in low‐ and middle‐income countries, optimal management of HPV‐positive women remains undetermined, particularly in resource‐limited settings. Here, using data from the 3T study involving women in Cameroon, the authors evaluated the ability of extended HPV ...
Micol Murtas   +11 more
wiley   +1 more source

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