Developmental pathways to autism in tuberous sclerosis complex: Evidence from a longitudinal cohort
Abstract The association between autism spectrum disorder (hereafter referred to as autism) and tuberous sclerosis complex (TSC) is well established, yet the developmental pathways linking genetic mutation, cortical pathology, and epilepsy with autism remain unclear. The Tuberous Sclerosis 2000 Study recruited children newly diagnosed with TSC (N = 125)
Fiona S. McEwen +12 more
wiley +1 more source
Fish Assemblages Distinguish Eco-Friendly from Conventional Rice Paddies Through Abundance and Biomass Rather than Diversity. [PDF]
Lee BM, Kim MH, Choi SK, Eo J, Jun SM.
europepmc +1 more source
Theory of mind: A cognitive endophenotype of juvenile myoclonic epilepsy?
Abstract Objective Juvenile myoclonic epilepsy (JME), the most common idiopathic generalized epilepsy, is associated with neuropsychological and psychiatric comorbidities, including social cognition and theory of mind (ToM) deficits. The interplay between clinical features, social cognition, and their neural and genetic substrates remains poorly ...
Bernardo Crespo‐Pimentel +13 more
wiley +1 more source
Ternary composite amendments of sludge-humic acid-fertilizer for mineral mud paddy field utilization. [PDF]
Zhu Z +5 more
europepmc +1 more source
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout +14 more
wiley +1 more source
Beyond the Paddy Fields: Riparian Reed Beds as Essential Natural Habitat for the Critically Endangered Suweon Treefrog, <i>Dryophytes suweonensis</i>. [PDF]
Koo KS, Park EJ, Jin SN, Yun KS.
europepmc +1 more source
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout +20 more
wiley +1 more source
Water Level Regulation Regime Shifts Drive Divergent Foraging Habitat Use by Wintering Hooded Cranes (<i>Grus monacha</i>) in Shallow Gate-controlled Lakes of the Yangtze Floodplain. [PDF]
Fang Y, Zhong Y, Zhou L, Liang M.
europepmc +1 more source
Abstract Objective To evaluate the effectiveness and tolerability of cenobamate in patients with a significant reduction in concomitant antiseizure medication (ASM) in European cenobamate Early Access Programs (EAPs). Method Anonymized patient data from real‐world studies/registries associated with European cenobamate EAPs were pooled.
Vicente Villanueva +25 more
wiley +1 more source
Draft genome sequence of <i>Pantoea stewartii</i> subsp. <i>indologenes</i> strain UIA 44 isolated from discolored rice grain in a paddy field of Penang, Malaysia. [PDF]
Syd Abdul Rahman SSM +6 more
europepmc +1 more source

