Results 111 to 120 of about 123,268 (305)

Data linkage errors in hospital administrative data when applying a pseudonymisation algorithm to paediatric intensive care records. [PDF]

, 2015
OBJECTIVES: Our aim was to estimate the rate of data linkage error in Hospital Episode Statistics (HES) by testing the HESID pseudoanonymisation algorithm against a reference standard, in a national registry of paediatric intensive care records. SETTING:
Academy of Medical Royal Colleges, Barry, Chassin, Connecting for Health, Dattani, Department of Communities and Local Government, Fellegi, Fraser, Goldstein, Goldstein, Gray, Hagger-Johnson, Harron, Health and Social Care Information Centre, Health and Social Care Information Centre, Health and Social Care Information Centre, Health and Social Care Information Centre, Health and Social Care Information Centre, Health and Social Care Information Centre, Health and Social Care Information Centre, Jaro, Lariscy, Moore, Office of National Statistics, Paediatric Intensive Care Audit Network (PICANet), Royal College of Obstetricians and Gynaecologists, Schmidlin, Schnell, Secretary of State, Suresh   +29 more
core   +4 more sources

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Dynamic versus fixed cerebral perfusion pressure targets in paediatric traumatic brain injury: a STARSHIP analysisResearch in context

EClinicalMedicine
Summary: Background: Cerebral perfusion pressure (CPP) represents a key target for intensive care management of paediatric traumatic brain injury (TBI) patients. Current guidelines recommend a CPP target within the range of 40–50 mmHg but emphasise that
C.A. Smith, S.Y. Bögli, M.M. Placek, M. Cabeleira, D. White, E. Daubney, A. Young, E. Beqiri, R. Kayani, R. O'Donnell, N. Pathan, S. Watson, A. Maw, M. Garnett, H.K. Kanthimathinathan, H. Bangalore, S. Sundararajan, G. Subramanian, D. Raffaj, S. Lampariello, A. Sarfatti, A. Mayer, O. Ross, M. Czosnyka, P.J. Hutchinson, P. Smielewski, S. Agrawal, Shruti Agrawal, Peter Smielewski, Peter J. Hutchinson, Stefan Yu Bögli, Claudia A. Smith, Carly Tooke, Caroline Payne, Holly Belfield, Amisha Mistry, Collette Spencer, Claire Jennings, Lara Bunni, Laura Anderson, Emily Morgan, Melanie James, Rebecca Beckley, Tahnima Khatun, Hafiza Khatun, Olivia Nugent, Richard Aldridge, Ruth Morgan, Julie Morcombe, Martin Quinton, Catherine Postlethwaite, Jenny Pond, Jessica Cutler, Caitlin Oxford, Marek Czosnyka, Michal Placek, Manuel Cabaleira, Deborah White, Esther Daubney, Adam Young, Erta Beqiri, Riaz Kayani, Roddy O'Donnell, Nazima Pathan, Suzanna Watson, Anna Maw, Matthew Garnett, Hari Krishnan Kanthimathinathan, Harish Bangalore, Santosh Sundararajan, Gayathri Subramanian, Dusan Raffaj, Simona Lampariello, Avishay Sarfatti, Anton Mayer, Oliver Ross   +75 more
doaj   +1 more source

Access via the internal jugular vein [PDF]

, 2008
Central venous access via the internal jugular vein (IJV) is safe, relatively easy and very commonly used in infants and children undergoing cardiac surgery for congenital heart disease. Because of the wide range of anatomical variations an ultrasound-
Kruessell, Markus, Sreeram, Narayanswami, Trieschmann, U., Udink ten Cate, Floris   +3 more
core  

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III, Tejaswi Nori, Alex I. Halpern, Hannah LaPadula, Arthur V. Cresce, Sarah L. Wright, Anthony D. Sandler, Peter Kofinas   +7 more
wiley   +1 more source

Cardiac-related neonatal collapse presenting to the emergency department: a retrospective cohort study

BMJ Paediatrics Open
Background To describe the characteristics of cardiac-related neonatal collapses referred to a critical care transport service and evaluate the diagnostic accuracy and management at referral and retrieval.Methods Retrospective cohort analysis of cardiac ...
Jon Lillie, Manson Chon In Kuok, Jennie Lambert, Anitha Janjanam   +3 more
doaj   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Development and internal validation of a clinical prediction model for the needed level of care in preterm neonates

BMC Pediatrics
Purpose To address capacity problems at tertiary-level neonatal intensive care units (NICUs) within current staffing limitations, our study aims to demonstrate the feasibility of identifying very preterm neonates not in need of highly specialised ...
Josephine H. L. Wagenaar, Marte Broekhoven, Arie Franx, Maaike S. Kleinsmann, Irwin K. M. Reiss, Hendrik Rob Taal   +5 more
doaj   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source