Results 41 to 50 of about 2,576 (161)

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

Anthocyanin Accumulation and Differential Expression of the Biosynthetic Genes Result in a Discrepancy in the Red Color of Herbaceous Peony (Paeonia lactiflora Pall.) Flowers

Horticulturae, 2022
Herbaceous peony (Paeonia lactiflora Pall.) is an ornamental plant with huge potential in the international flower market. Similar to the flowers of most other ornamental plants, the top sellers of P.
Yanqing Wu, Zhaojun Hao, Yuhan Tang, Daqiu Zhao   +3 more
doaj   +1 more source

Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis

eFood, Volume 7, Issue 3, June 2026.
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng, Yanqun Luo, Ying Gao, Yi Su, Haiping Xue, Tao Wu   +5 more
wiley   +1 more source

Protein Tyrosine Phosphatase 1B‐Mediated Granulosa Cell Insulin Resistance Links Metabolic Stress to Aging‐Relevant Ovarian Dysfunction and Is Reversed by Gengnianchun

Aging Cell, Volume 25, Issue 6, June 2026.
Metabolic stress induces insulin resistance and upregulates PTP1B in granulosa cells, leading to aging‐relevant ovarian dysfunction. Gengnianchun (GNC) suppresses PTP1B, restores IRS1–AKT2–GLUT4 signaling, and preserves follicles, highlighting PTP1B as a therapeutic target for ovarian dysfunction in metabolically vulnerable states.
Yanqiu Rao, Ting Xu, Yan Ding, Jun Li, Lingyun Gao, Yun Wang, Wenjun Wang   +6 more
wiley   +1 more source

Progress in the Study of Chemical Structure and Pharmacological Effects of Total Paeony Glycosides Isolated from Radix Paeoniae Rubra

Current Issues in Molecular Biology
Radix paeoniae rubra, known as red peony root, is derived from the dried roots of Paeonia lactiflora pall or Paeonia veitchii lynch from the Ranunculaceae family. It is recognized for its properties of clearing heat, cooling blood, dispelling stasis, and
Yumu Sun, Taiyu Liu, Xueying Zhao
doaj   +1 more source

Herbaceous Peony (Paeonia lactiflora Pall.) as an Alternative Source of Oleanolic and Ursolic Acids

International Journal of Molecular Sciences, 2011
Oleanolic acid (OA) and ursolic acid (UA) have been proven to possess many biological activities, and much attention is focused on the search for plants which are rich in OA and UA. In this report, the OA and UA accumulation characteristics were investigated in 47 cultivars of Chinese herbaceous peony (Paeonia lactiflora Pall.) and were followed in ...
Zhou, Chunhua, Zhang, Ying, Sheng, Yanle, Zhao, Daqiu, Lv, Sansan, Hu, Yue, Tao, Jun   +6 more
openaire   +2 more sources

Xuming Zhusan Decoction Attenuates Post‐Stroke via Modulating TLR4/MYD88/NF‐κB Pathway in Mice

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
High‐dose Xuming Zhusan (XMZS) improves neurological/cognitive functions and reduces cerebral infarct in MCAO mice. It inhibits microglial activation and pro‐inflammatory cytokines via suppressing the TLR4/MYD88/NF‐κB pathway, protecting neurons. ABSTRACT Ischemic stroke induces neuroinflammation that exacerbates neuronal damage.
Xi Liu, Cheng Wang, Ling Han, Yi'an Xiao, Hanchang Yu, Zhongxu Hu, Xiyun Fei, Min Peng, Jilin Zhou, Zhijun Zhong   +9 more
wiley   +1 more source

Jiawei Danxuan Koukang and Its Component Kaempferol Alleviate Oral Submucous Fibrosis by Restoring Epithelial‐Fibroblast Homeostasis and Suppressing Neutrophil Recruitment via the ANXA1/FPR2 Axis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
JDK and kaempferol upregulate ANXA1 in oral epithelia, which bind to fibroblast FPR2 to suppress myofibroblast activation, and collagen deposition, while reducing neutrophil recruitment and inflammation, thereby restoring epithelial‐fibroblast homeostasis to alleviate arecoline‐induced OSF. ABSTRACT Oral submucous fibrosis (OSF) is a betel quid chewing‐
Yao Xiao, Yisi Tan, Yanli Liu, Ruiyi Chen, Tao Zhou, Zhaoyong Hu, Jin Tan   +6 more
wiley   +1 more source

Tongxinluo for the Secondary Prevention of Atherosclerotic Disease: A Systematic Review and Meta‐Analysis of Randomized Clinical Trials

Brain and Behavior, Volume 16, Issue 3, March 2026.
This systematic review and meta‐analysis aims to evaluate the efficacy of tongxinluo in the secondary prevention of atherosclerotic cardiovascular disease (ASCVD). In summary, among patients with ASCVD, tongxinluo was associated with a trend toward a reduced incidence of stroke and a 28% lower risk of major adverse cardiovascular events (MACE), which ...
Yanyan Feng, Zhaobo Shi, Jiewen Zhang, Jiejie Li   +3 more
wiley   +1 more source

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 3, March 2026.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source