Results 51 to 60 of about 2,576 (161)

Identification of key genes for triacylglycerol biosynthesis and storage in herbaceous peony (Paeonia lactifolra Pall.) seeds based on full-length transcriptome

BMC Genomics
Background The herbaceous peony (Paeonia lactiflora Pall.) is extensively cultivated in China due to its root being used as a traditional Chinese medicine known as ‘Radix Paeoniae Alba’.
Huajie Xu, Miao Li, Di Ma, Jiajun Gao, Jun Tao, Jiasong Meng   +5 more
doaj   +1 more source

Therapeutic Potential of Saikosaponins in MASLD and Cross‐Organ Protection: A Research Update

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
This review systematically outlines the multi‐target mechanisms of Saikosaponins (SSs) against MASLD, encompassing the regulation of lipid metabolism, insulin resistance, and inflammatory response. Furthermore, it highlights their novel cross‐organ protective effects on the cardiovascular, renal, and central nervous systems, providing therapeutic ...
Jiayao Xiong, Wanyan Tan, Ze Jin, Xiangyu Li, Yuting Chen, Wanting Xie   +5 more
wiley   +1 more source

Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Paning I decoction alleviated neuroinflammation in Parkinson's disease. ABSTRACT Background Parkinson's disease (PD) is a major neurodegenerative disorder. Some patients show limited response to standard therapies, driving the need for new complementary treatments.
Yan‐Jun Chen, Jing‐Wen Chen, Ming‐Rong Xie, Rui‐Zhen Wang, Yu‐Ling Wan, Jie Zeng, Bing‐Wu Zhong, Sheng‐Qiang Zhou, Fang Liu   +8 more
wiley   +1 more source

Comprehensive Microbiome and Metabolome Analyses Reveal the Medicinal Components of Paeonia lactiflora

Plants, 2023
Paeonia lactiflora Pall. is not only a traditional ornamental plant, but also an important medicinal plant. Currently, some P. lactiflora cultivars are used for ornamental purposes, but their potential medicinal value is ignored. To explore the medicinal
Liping Yang, Mengdi Zhou, Mengting Zu, Jiajia Zuo, Yingdan Yuan   +4 more
doaj   +1 more source

Synergistic Effects of Compound Dendrobium Candidum and Antihypertensive Medications on Refractory Hypertension in Spontaneously Hypertensive Rats

Cardiology Research and Practice, Volume 2026, Issue 1, 2026.
Background Compound dendrobium candidum (CDC) is formulated from Dendrobium candidum and fragrant peony. Preliminary studies have demonstrated that the combination of CDC with conventional antihypertensive medications exhibits significant synergistic effects in lowering blood pressure.
Xiaoyu Chen, Cheng Tong, Jie Wang, Yue Wu, Tuo Feng, Jing Wang, Zedong Gong, Yingzhi Chen, Shiyong Chen, Xiaoming Jin, Sisi Chen, Zhongxiu Guo, Xuan Chen, Zeming Ren, Guanhai Dai, Yeling Tong, Xiyu Mei, Renzhao Wu, Xiaomin Xue, Dafeng Yang   +19 more
wiley   +1 more source

Role of Chinese Botanical Drugs in the Adjuvant Treatment of Helicobacter pylori Infection: An Umbrella Review of the Evidence of Randomized Controlled Trials

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Aim To evaluate the quality of evidence, potential biases, and validity of all available meta‐analyses about the Chinese botanical drug treatment for the Helicobacter pylori (Hp) infection. Materials and Methods A comprehensive search of six electronic databases (PubMed, Embase, Web of Science, Cochrane Database of Systematic Reviews, CNKI, Wanfang ...
Yuege Yang, Xiaoyan Jiang, Baofu Lin, Chunhong Zhang, Donghou Liu, Marta Laranjo   +5 more
wiley   +1 more source

Efficacy of Jia Wei Shoutai Wan Combined With Dydrogesterone in the Treatment of Threatened Abortion Complicated With Endometrial Cavity Fluid: A Prospective, Single‐Center, Randomized Controlled Trial

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Objective This study aimed to evaluate the clinical efficacy of Jia Wei Shoutai Wan (JWSTW) combined with dydrogesterone in patients with threatened abortion (TA) complicated by endometrial cavity fluid (ECF). Methods This was a prospective, single‐center, randomized controlled trial.
Yongrong Zhang, Huan Wei, Hui Li, Yu Zhang, Fang Jia, Vikas Kumar Roy   +5 more
wiley   +1 more source

Modified Guizhi Plus Huangqi Decoction Improves Antiphospholipase A2 Receptor Antibody–Induced Podocyte Injury Through Modulating Autophagy‐Related Markers via AMPK/mTOR Pathway

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background Phospholipase A2 receptor (PLA2R)–associated membranous nephropathy (MN) is a primary cause of nephrotic syndrome in adults. Modified Guizhi plus Huangqi decoction (MGPHD) has been clinically effective for PLA2R MN. This basic study was designed to investigate the efficacy and mechanisms of MGPHD in treating PLA2R MN.
Manxia Huang, Yangpu Li, Zhishu Yang, Yunxin Lin, Zhuoting Liu, Zilan Jiang, Tingting Tan, Xinhui Liu, Youjia Zeng, Yue Xu   +9 more
wiley   +1 more source

Qiling Hushen Formula Ameliorates Type 2 Diabetic Kidney Disease via Gut‐Kidney Axis Restoration and TLR4/NF‐κB/NLRP3 Suppression

Journal of Diabetes Research, Volume 2026, Issue 1, 2026.
Context Qiling Hushen Formula (QLHSF) has been widely used in clinical treatment for Type 2 diabetic kidney disease (T2DKD), yet its mechanism remains unclear. Objective This study is aimed at elucidating the protective effects and mechanisms of QLHSF on T2DKD mice.
Yuxin Wang, Pei Sheng, Xue Wang, Min Lin, Wentao Cai, Shiyao Wei, Yuyun Du, Ming Yan, Lei Wang, Xiaofei An, Haoqiang Zhang   +10 more
wiley   +1 more source

Qinggan Mingshi Granules Inhibited Ferroptosis to Treat Diabetic Retinopathy in Mice Through NRF2/GPX4 Axis

Journal of Diabetes Research, Volume 2026, Issue 1, 2026.
Background Diabetic retinopathy (DR) is a common microvascular complication of diabetes, which seriously affected the life quality in diabetic patients. Developing novel therapy to improve DR is essential. Qinggan Mingshi granules (QGMS) have been demonstrated with protective effects on DR clinically.
Zhongyong Zhang, Qianqian Jin, Hongmin Zhao, Yingkai Liu, Meng Wang, Zhongqian Han, Jin Wu, Shuquan Lv, Xiaoyun Wang, Wei Chen, Qingjin Wang, Hailong Bai, Yuansong Wang, Weibo Wen   +13 more
wiley   +1 more source