Results 211 to 220 of about 60,638 (288)

Platelet Activating Factor (PAF): A Mediator of Inflammation

BioFactors, 2022
Platelet‐activating factor (PAF) is a phospholipid‐derived mediator with an established role in multiple inflammatory states. PAF is synthesized and secreted by multiple cell types and is then rapidly hydrolyzed and degraded to an inactive metabolite ...
Julia Upton
exaly   +2 more sources

PAF‐6 Doped with Phosphoric Acid through Alkaline Nitrogen Atoms Boosting High‐Temperature Proton‐Exchange Membranes for High Performance of Fuel Cells

Advances in Materials, 2023
High‐temperature proton‐exchange‐membrane fuel cells (HT‐PEMFCs) can offer improved energy efficiency and tolerance to fuel/air impurities. The high expense of the high‐temperature proton‐exchange membranes (HT‐PEMs) and their low durability at high ...
Liying Wang, Yuliang Wang, Zhangnan Li, Tianyang Li, Ruyu Zhang, Jing Li, Baijun Liu, Zhongyuan Lv, Weiwei Cai, Shuhui Sun, Wei Hu, Yunfeng Lu, G. Zhu   +12 more
semanticscholar   +1 more source

PAF and PAF acetylhydrolase in the nervous system

Journal of Lipid Mediators and Cell Signalling, 1996
PAF acetylhydrolase is a key enzyme of PAF inactivation. Intracellular PAF acetylhydrolase isoform Ib is a heterotrimeric enzyme composed of alpha-, beta- and gamma-subunits. The beta- and gamma-subunits act as a catalytic unit and their amino acid sequences are homologous.
M, Hattori, J, Aoki, H, Arai, K, Inoue
openaire   +2 more sources

PAF-acetylhydrolases

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1999
Platelet-activating factor acetylhydrolases (PAF-AHs, EC 3.1.1.47) constitute a unique subfamily of phospholipases A(2), specific for short acyl chains in the sn-2 position of the phospholipid. Their primary substrate is the platelet-activating factor, PAF, from which they cleave an acetyl moiety with concomitant release of lysoPAF.
Z S, Derewenda, Y S, Ho
openaire   +2 more sources

Synthesis of a PAF Immunogen and Production of PAF-Specific Antibodies

Lipids, 1991
AbstractPlatelet activating factor (PAF), a naturally occurring phospholipid with many potent physiological and pharmacological activities, is implicated as a mediator of many diseases. An immunoassay for PAF would greatly improve quantitation, and hence PAF‐specific antibodies were required.
M A, Smal, B A, Baldo, J W, Redmond
openaire   +2 more sources

Platelet activating factor (PAF) and activity of its biosynthetic and catabolic enzymes in blood and leukocytes of male patients with newly diagnosed heart failure

Clinical Biochemistry, 2009
Demosthenes Panagiotakos, Christina Chrysohoou, Smaragdi Antonopoulou   +2 more
exaly   +2 more sources

Pulmonary vascular reactivity: effect of PAF and PAF antagonists

Journal of Applied Physiology, 1992
We investigated the effects of two different platelet-activating factor (PAF) antagonists, SRI 63–441 and WEB 2086, on PAF-, angiotensin II-, and hypoxia-induced vasoconstrictions in isolated rat lungs perfused with a physiological salt solution. Bolus injection of PAF (0.5 micrograms) increased pulmonary arterial and microvascular pressures and ...
C R, Chen, N F, Voelkel, S W, Chang
openaire   +2 more sources