Results 201 to 210 of about 49,971 (287)

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta   +2 more
wiley   +1 more source

Evaluation of Nurses' Intent to Leave: Italian Translation, Cultural Adaptation, and Initial Psychometric Assessment of the Anticipated Turnover Scale

open access: yesNursing Open, Volume 13, Issue 10, October 2026.
ABSTRACT Aim The aim of this study was to translate, culturally adapt, and preliminarily validate the Italian version of the Anticipated Turnover Scale (ATS). Design Cross‐sectional validation study. Methods The Italian version of the ATS instrument was evaluated in a non‐probabilistic sample of 168 nurses working at a Northeastern Italian Public ...
Sara Cignola   +2 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Disease and Genetic Risk in Germany—An Observational Real‐World Cohort Study

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 8, October 2026.
ABSTRACT Background Metabolic dysfunction‐associated steatotic disease (MASLD) affects increasing numbers of patients worldwide. The PNPLA3 p.I148M variant represents a major genetic determinant of MASLD progression. The loss‐of‐function HSD17B13 polymorphism rs72613567 was reported in turn to be hepatoprotective.
Marcin Krawczyk   +19 more
wiley   +1 more source

MitoNumt: A Workflow for Recovering Mitochondrial Genomes From Long‐Read Data and Detecting NUMT Contamination in Mitochondrial Genome Assemblies

open access: yesMolecular Ecology Resources, Volume 26, Issue 7, October 2026.
ABSTRACT Nuclear mitochondrial DNA segments (NUMTs) are genomic DNA fragments that originate from historical insertions of mitochondrial DNA sequences into the nuclear genome. During mitochondrial genome (mtgenome) assembly from short‐read genome sequencing data, NUMT fragments may be misidentified and incorporated into mtgenome assemblies, leading to ...
Ruidong Cao, Tong Xin, Yubo Hao, Yibo Hu
wiley   +1 more source

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