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Advances in Materials, 2023
High‐temperature proton‐exchange‐membrane fuel cells (HT‐PEMFCs) can offer improved energy efficiency and tolerance to fuel/air impurities. The high expense of the high‐temperature proton‐exchange membranes (HT‐PEMs) and their low durability at high ...
Liying Wang +12 more
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High‐temperature proton‐exchange‐membrane fuel cells (HT‐PEMFCs) can offer improved energy efficiency and tolerance to fuel/air impurities. The high expense of the high‐temperature proton‐exchange membranes (HT‐PEMs) and their low durability at high ...
Liying Wang +12 more
semanticscholar +1 more source
Platelet Activating Factor (PAF): A Mediator of Inflammation
Biofactors, 2022Platelet‐activating factor (PAF) is a phospholipid‐derived mediator with an established role in multiple inflammatory states. PAF is synthesized and secreted by multiple cell types and is then rapidly hydrolyzed and degraded to an inactive metabolite ...
J. Upton +3 more
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Methods matter: population attributable fraction (PAF) in sport and exercise medicine
British Journal of Sports Medicine, 2020Physical inactivity kills as many people as smoking —a newspaper heading reads1 following a Lancet publication2 suggesting that more than 5 million deaths would be avoided annually if all inactive people exercised.
A. Khosravi, R. Nielsen, M. Mansournia
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Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1999
Platelet-activating factor acetylhydrolases (PAF-AHs, EC 3.1.1.47) constitute a unique subfamily of phospholipases A(2), specific for short acyl chains in the sn-2 position of the phospholipid. Their primary substrate is the platelet-activating factor, PAF, from which they cleave an acetyl moiety with concomitant release of lysoPAF.
Z S, Derewenda, Y S, Ho
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Platelet-activating factor acetylhydrolases (PAF-AHs, EC 3.1.1.47) constitute a unique subfamily of phospholipases A(2), specific for short acyl chains in the sn-2 position of the phospholipid. Their primary substrate is the platelet-activating factor, PAF, from which they cleave an acetyl moiety with concomitant release of lysoPAF.
Z S, Derewenda, Y S, Ho
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PAF and PAF acetylhydrolase in the nervous system
Journal of Lipid Mediators and Cell Signalling, 1996PAF acetylhydrolase is a key enzyme of PAF inactivation. Intracellular PAF acetylhydrolase isoform Ib is a heterotrimeric enzyme composed of alpha-, beta- and gamma-subunits. The beta- and gamma-subunits act as a catalytic unit and their amino acid sequences are homologous.
M, Hattori, J, Aoki, H, Arai, K, Inoue
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PAF Receptor And “Cache-Oreilles” Effect. Simple PAF Antagonists
Lipids, 1991AbstractNine simple and structurally flexible PAF antagonists were synthesized and their inhibitory effects on PAF induced platelet aggregation were measured. Compounds with PAF antagonistic activity exhibited a negative electrostatic potential generated by two trimethoxyphenyl groups (isocontour at −10 Kcal/mole) at various distances between the ...
J, Lamotte-Brasseur +8 more
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Pulmonary vascular reactivity: effect of PAF and PAF antagonists
Journal of Applied Physiology, 1992We investigated the effects of two different platelet-activating factor (PAF) antagonists, SRI 63–441 and WEB 2086, on PAF-, angiotensin II-, and hypoxia-induced vasoconstrictions in isolated rat lungs perfused with a physiological salt solution. Bolus injection of PAF (0.5 micrograms) increased pulmonary arterial and microvascular pressures and ...
C R, Chen, N F, Voelkel, S W, Chang
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