Results 71 to 80 of about 1,433,501 (267)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Political Imaginary after Neo- Liberalism: Populism and the Return of ‘Elemental Politics’
Im@go. A Journal of the Social Imaginary, 2020 In this paper, I claim that Carl Schmitt's enigmatic work Land and Sea provides contemporary philosophers and social theorists with important insights into what appears to be an emergent, post-neo-liberal, political imaginary.
Neil Turnbull
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Imaginaires diaboliques, mythes millénaristes et violences religieuses
Im@go. A Journal of the Social Imaginary, 2017 Diabolic Imaginaries, Millenarian Myths and Religious Violence. The current phase of millenarism reactivation in the wake of Islamic fundamentalism shows clearly the strength of the imaginary of Evil.
Jean-Jacques Wunenburger
doaj
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Im@go. A Journal of the Social Imaginary, 2017 Imagining the Evil. The essay aims to walk along the way to the symbolic richness of Evil, starting from a critique of the Spaltung. Contemporary malign manifestations will be explored with the aid of Durand’s coincidentia oppositorum hermeneutics, in ...
Fabio D'Andrea, Antonio Tramontana
doaj
Global Cardiology Science and Practice[first paragraph of article] This month marks 13 years of the journal's existence. In this period the journal's policy has been devoted to present the latest developments in cardiology and cardiac surgery in an easily accessible form, with an emphasis on global issues and equity in healthcare delivery.
openaire +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Pouvoir politique et puissance populaire
Im@go. A Journal of the Social Imaginary, 2020 Political authority and popular power. The article aims at identifying the deep roots of populism in the divide between political authority and popular power.
Michel Maffesoli
doaj
American Journal of Preventive Cardiology, 2020 Sergio Fazio, Nathan D. Wong
openaire +7 more sources