Results 81 to 90 of about 229 (147)

Comprehensive management of vulvovaginal cancers

CA: A Cancer Journal for Clinicians, Volume 75, Issue 5, Page 410-435, September/October 2025.
Abstract Vulvar and vaginal cancers represent rare malignancies, with an incidence of 2.7 per 100,000 women for vulvar cancer, predominantly affecting women older than 60 years, although rising rates are observed in younger demographics. Approximately 90% of vulvar cancers are squamous cell carcinoma and frequently are associated with human ...
Angélica Nogueira‐Rodrigues, Maaike H. M. Oonk, Domenica Lorusso, Brian Slomovitz, Mario M. Leitão Jr, Glauco Baiocchi   +5 more
wiley   +1 more source

Mammary-like adenocarcinoma of the vulva associated to Paget’s disease: a case report [PDF]

, 2016
Mammary-like adenocarcinoma of the vulva associated to Paget's disease is exceedingly rare. So, it is very important to perform all the pathological and immunohistochemical investigations to achieve differential  diagnosis from both a metastatic lesion ...
Kouira, Mouna, Meddeb, Sawsen, Rhim, Mohamed Salah, Bibi, Mohamed, Khairi, Hedi, Yacoubi, Mohamed Tahar, Mestiri, Sarra   +6 more
core   +1 more source

Cancer of the vulva: 2025 update

International Journal of Gynecology &Obstetrics, Volume 171, Issue S1, Page 36-47, September 2025.
Abstract Vulvar cancer is an uncommon gynecological malignancy primarily affecting postmenopausal women. No specific screening exists and the most effective strategy to reduce the incidence of vulvar cancer is the opportune treatment of predisposing and preneoplastic lesions associated with its development.
Alexander B. Olawaiye, Mauricio A. Cuello, Sushil Beriwal, Linda J. Rogers   +3 more
wiley   +1 more source

Apocrine adenocarcinoma of the vulva

Rare Tumors, 2013
Cutaneous vulvar carcinomas are predominantly of squamous cell carcinoma type. Primary vulvar adenocarcinomas are rare with a poorly understood histogenesis.
Babita Kajal, Hetal Talati, Dean Daya, Salem Alowami   +3 more
doaj   +1 more source

Paget disease.Three cases of mammary Paget disease.

Skin Cancer, 1991
最近10年間に当科で経験した乳房Paget病の3例を報告した。症例1は34歳女性, 右乳頭とその周辺の硬く腫脹した紅色局面。症例2は69歳女性, 点状の鱗屑を付する右乳頭の腫脹。症例3は64歳女性, 左乳頭と周辺乳輪に厚い痂皮を付する紅色局面。組織学的に症例1, 2は面皰癌の所見が認められたが, 症例3は異型な乳管を認めるのみであった。症例2は臨床的に湿疹様の軽微な変化しか呈しておらず早期の生検の必要性を認識した。
openaire   +2 more sources

Fibronectin Fibers Progressively Lose Their Tension in Invasive Human Breast Carcinoma while Being Tensed in DCIS and Healthy Breast Tissue

Advanced Science, Volume 12, Issue 31, August 21, 2025.
Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville, Charlotte M. Fonta, Cornelia Leo, Lucine Christe, Jörg Goldhahn, Gad Singer, Viola Vogel   +6 more
wiley   +1 more source

Adenomatose erosiva do mamilo Erosive adenomatosis of the nipple

Anais Brasileiros de Dermatologia, 2011
A adenomatose erosiva do mamilo é uma complexa proliferação benigna mamária que pode ser confundida com neoplasias malignas da mama. A apresentação típica cursa com descarga mamária, eritema, erosão e formação de crostas.
Mayara Schulze Cosechen, Adma Silva de Lima Wojcik, Flávio Meingast Piva, Betina Werner, Sérgio Zuneda Serafini   +4 more
doaj   +1 more source

Establishment and characterization of breast cancer organoids from a patient with mammary Paget’s disease

Cancer Cell International, 2020
Background Mammary Paget’s disease (MPD) is an uncommon cutaneous intraepithelial malignancy with ulceration of the nipple or areola. Its pathogenesis and genomic mutation remain largely unknown and no cell lines are established from primary tumors ...
Bo Pan, Dongyi Zhao, Yaqian Liu, Na Li, Chen Song, Ning Li, Xuelu Li, Man Li, Zuowei Zhao   +8 more
doaj   +1 more source

Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded

MedComm, Volume 6, Issue 7, July 2025.
Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin, San‐yang Yu, Jia‐lu Gao, Jian‐fei Yan, Qian‐qian Wan, Shuai‐lin Jia, Franklin Tay, Kai Jiao, Lina Niu   +8 more
wiley   +1 more source

Mammary Paget's Disease as a Sign of Local Recurrence Two Decades Following Breast Conservation and Adjuvant Therapy for Early Stage Breast Cancer [PDF]

Reports of mammary Paget's disease (MPD) as a manifestation of breast cancer recurrence are rare. MPD presents a particular challenge when emerging more than two decades after a breast cancer treated with evidence-based therapy. There is a broad spectrum
Afzal, RJ, Anderson, BM, Xu, J, Basree, MM, Wilke, LG, Howard, SP   +5 more
core   +1 more source