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Paget's disease of bone [PDF]

BMJ, 1981
The essential requirement for effective treatment of Paget’s disease of bone is that the characteristic abnormality of bone remodelling is predictably corrected without the occurrence of significant side effects. Although the ideal agent is not currently available, appropriate use of the calcitonins or diphosphonates goes a long way to achieving this ...
openaire   +2 more sources

Radiological impact of oral bisphosphonate use on polyostotic Paget's disease of bone over a 2 year period

Radiology Case Reports
Paget's disease of bone is a disorder of osteoclasts which hampers the physiological process of bone remodeling. It is the most common metabolic orthopedic disease in the Caucasian populace; we report the diagnosis of Paget's disease of bone in a South ...
Christopher Jude Pinto, MD, Shadab B. Maldar, MD, Siddhi Hegde, MD, Sharanabasav M. Choukimath, MD   +3 more
doaj   +1 more source

Clinical features and treatment of perianal Paget’s disease: with report of five cases

结直肠肛门外科
Perianal Paget’s disease, also known as perianal eczema-like carcinoma, is a relatively rare malignant disease that can be clinically categorized into primary and secondary perianal Paget’s disease. The disease is highly invasive and clinically difficult
Liu Yaoan, Ye Xiaorui, Yang Yang, Jin Heiying   +3 more
doaj   +1 more source

Poorly differentiated high-grade urothelial carcinoma presenting as Paget's disease of the vulva with no overt urinary tract neoplasm detected

Gynecologic Oncology Reports, 2017
Objective: There are few reported cases of secondary (non-cutaneous) vulvar Paget's disease related to urothelial carcinoma (UC), with only 7 of them presenting initially with Paget's disease and up to a 13-year lapse from detecting a urinary tract ...
Radha R. Padhy, Niloo Nasseri-Nik, Fouad Abbas   +2 more
doaj   +1 more source

Paget's disease of bone - becoming a rarity?

, 2009
Objectives. Paget's disease is a chronic bone disorder of unknown cause. Recent studies have reported an unexplained reduction in both prevalence and disease severity.
Gamble, Gregory, Bastin, S, Bird, H, Cundy, Timothy   +3 more
core   +1 more source

Paget’s Breast Disease: A Case Report and Review of the Literature

Frontiers in Surgery, 2017
Paget’s disease of the breast is a rare cancer. This typical clinical case illustrates the different epidemiological, clinical, histological, therapeutic, and evolving aspects of the disease. We report a case of Paget’s disease in a 43-year-old woman who
S. Dubar, M. Boukrid, Jean Bouquet de Joliniere, L. Guillou, Quoc Duy Vo, A. Major, N. Ben Ali, F. Khomsi, A. Feki   +8 more
doaj   +1 more source

Paget′s disease of the breast

Journal of Carcinogenesis, 2011
Paget's disease of the breast is a rare type of cancer of the nipple-areola complex and that is often associated with an underlying in situ or invasive carcinoma. This article provides an overview and we review the main clinicopathological and therapeutic features of mammary Paget's disease.
openaire   +2 more sources

Mammary-like adenocarcinoma of the vulva associated to Paget's disease: a case report

The Pan African Medical Journal, 2014
Mammary-like adenocarcinoma of the vulva associated to Paget's disease is exceedingly rare. So, it is very important to perform all the pathological and immunohistochemical investigations to achieve differential diagnosis from both a metastatic lesion ...
Sawsen Meddeb, Mohamed Salah Rhim, Sarra Mestiri, Mouna Kouira, Mohamed Bibi, Hedi Khairi, Mohamed Tahar Yacoubi   +6 more
doaj   +1 more source

Extramammary Perianal Paget’s Disease

Case Reports in Gastroenterology, 2009
Perianal Paget’s disease is a rare malignancy. It is rarely isolated and often associated with an underlying adenocarcinoma. It usually presents with anal itchiness and discomfort and can be misdiagnosed as hemorrhoids.
M.N. Al Hallak, N. Zouain
doaj   +1 more source