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Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers.
Ornella Sari Cassol +5 more
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Extramammary Paget’s disease is a rare cutaneous malignant neoplasm, and few studies have described its radiological features. Herein, we report the case of an 83-year-old man with extramammary Paget’s disease and condyloma acuminatum.
Mana Shimomura, MD +9 more
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Paget’s Disease of Maxilla with Paranasal Sinuses: A Case Report [PDF]
Paget’s disease of bone is a chronic skeletal disorder affecting predominantly elderly individuals. The pelvic girdle is the most common site to be affected; however, other sites such as long bones, spine, and skull are also frequently affected.
Amurtham Veeramani +4 more
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The essential requirement for effective treatment of Paget’s disease of bone is that the characteristic abnormality of bone remodelling is predictably corrected without the occurrence of significant side effects. Although the ideal agent is not currently available, appropriate use of the calcitonins or diphosphonates goes a long way to achieving this ...
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Paget’s disease of the breast is often misdiagnosed. We report on a 72-year old patient with a history of 2.5 years without any malignant findings, followed by the identification of a bilateral Paget’s disease with bilateral breast cancers.
Dietrich Barth
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Paget's bone disease is a rare disease affecting the skeleton, inducing deformity and weakness of the affected bones and involving the splanchnocranium in only 8–23 % of all cases.
Olindo Massarelli +2 more
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Background Paget's disease is a metabolic disorder characterized by disorderly bone remodeling process of excessive osteoclastic and osteoblastic activities leading to a structurally disorganized appearance of the bone.
Muhammad Adib Abdul Onny +5 more
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Mithramycin in Paget's disease.
Mithramycin, a cytotoxic agent, has been used to treat 6 patients with severe symptomatic Paget's disease of bone. Bone pain improved dramatically. Side-effects included hypocalcaemia and nausea, but were not serious. Mithramycin is valuable in selected cases of Paget's disease.S. Afr. Med. J., 48, 1328 (1974).
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